Hmdb loader
Identification
HMDB Protein ID HMDBP12309
Secondary Accession Numbers None
Name 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase
Synonyms
  1. FO synthase subunit 1
Gene Name COFG
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
Pathways
  • Biosynthesis of cofactors
  • coenzyme F0 biosynthesis
  • Methane metabolism
  • Microbial metabolism in diverse environments
Reactions Not Available
GO Classification
Molecular Function
4 iron, 4 sulfur cluster binding
iron ion binding
transferase activity, transferring alkyl or aryl (other than methyl) groups
ammonia-lyase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 339
Molecular Weight 38258.12
Theoretical pI 4.801
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID A5UM12
UniProtKB/Swiss-Prot Entry Name COFG_METS3
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Samuel BS, Hansen EE, Manchester JK, Coutinho PM, Henrissat B, Fulton R, Latreille P, Kim K, Wilson RK, Gordon JI: Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut. Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10643-8. doi: 10.1073/pnas.0704189104. Epub 2007 Jun 11. [PubMed:17563350 ]