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Showing Protein 1-deoxy-D-xylulose 5-phosphate reductoisomerase (HMDBP12233)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 metabolite
Identification
HMDB Protein ID HMDBP12233
Secondary Accession Numbers None
Name 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Synonyms
  1. DXP reductoisomerase
  2. 1-deoxyxylulose-5-phosphate reductoisomerase
  3. 2-C-methyl-D-erythritol 4-phosphate synthase
Gene Name DXR
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
Pathways
  • Biosynthesis of secondary metabolites
  • isopentenyl diphosphate biosynthesis via DXP pathway
  • Terpenoid backbone biosynthesis
Reactions Not Available
GO Classification
Biological Process
isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process
Molecular Function
manganese ion binding
NADPH binding
1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 390
Molecular Weight 42741.945
Theoretical pI 5.48
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q8A684
UniProtKB/Swiss-Prot Entry Name DXR_BACTN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Xu J, Bjursell MK, Himrod J, Deng S, Carmichael LK, Chiang HC, Hooper LV, Gordon JI: A genomic view of the human-Bacteroides thetaiotaomicron symbiosis. Science. 2003 Mar 28;299(5615):2074-6. doi: 10.1126/science.1080029. [PubMed:12663928 ]