| Identification |
|---|
| HMDB Protein ID
| HMDBP12050 |
| Secondary Accession Numbers
| None |
| Name
| Neuronal acetylcholine receptor subunit alpha-4 |
| Synonyms
|
Not Available
|
| Gene Name
| CHRNA4 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Involved in neurotransmitter receptor activity |
| Specific Function
| After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane |
| Pathways
|
- 3-Methylthiofentanyl Action Pathway
- Alfentanil Action Pathway
- Alvimopan Action Pathway
- Anileridine Action Pathway
- Benzocaine Action Pathway
- Bupivacaine Action Pathway
- Buprenorphine Action Pathway
- Carfentanil Action Pathway
- Chloroprocaine Action Pathway
- Citalopram Action Pathway
- Cocaine Action Pathway
- Codeine Action Pathway
- Desipramine Action Pathway
- Dezocine Action Pathway
- Dibucaine Action Pathway
- Dihydromorphine Action Pathway
- Dimethylthiambutene Action Pathway
- Diphenoxylate Action Pathway
- Escitalopram Action Pathway
- Ethylmorphine Action Pathway
- Fentanyl Action Pathway
- Fluoxetine Action Pathway
- Heroin Action Pathway
- Hydrocodone Action Pathway
- Hydromorphone Action Pathway
- Imipramine Action Pathway
- Ketobemidone Action Pathway
- Levallorphan Action Pathway
- Levobupivacaine Action Pathway
- Levomethadyl Acetate Action Action Pathway
- Levorphanol Action Pathway
- Lidocaine (Local Anaesthetic) Action Pathway
- Mepivacaine Action Pathway
- Methadone Action Pathway
- Methadyl Acetate Action Pathway
- Morphine Action Pathway
- Nalbuphine Action Pathway
- Naloxone Action Pathway
- Naltrexone Action Pathway
- Nicotine Action Pathway
- Nicotine Metabolism Pathway
- Oxybuprocaine Action Pathway
- Oxycodone Action Pathway
- Oxymorphone Action Pathway
- Pentazocine Action Pathway
- Prilocaine Action Pathway
- Procaine Action Pathway
- Proparacaine Action Pathway
- Propoxyphene Action Pathway
- Remifentanil Action Pathway
- Ropivacaine Action Pathway
- Sufentanil Action Pathway
- Tramadol Action Action Pathway
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| 20q13.2-q13.3 |
| SNPs
| CHRNA4 |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 627 |
| Molecular Weight
| 69958.0 |
| Theoretical pI
| 7.21 |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
- 243-267↵275-293↵309-330↵601-619
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| 755648 |
| UniProtKB/Swiss-Prot ID
| P43681 |
| UniProtKB/Swiss-Prot Entry Name
| ACHA4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| L35901 |
| GeneCard ID
| CHRNA4 |
| GenAtlas ID
| CHRNA4 |
| HGNC ID
| HGNC:1958 |
| References |
|---|
| General References
| Not Available |
