| Identification |
|---|
| HMDB Protein ID
| HMDBP11713 |
| Secondary Accession Numbers
| None |
| Name
| Dolichol phosphate-mannose biosynthesis regulatory protein |
| Synonyms
|
Not Available
|
| Gene Name
| DPM2 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Regulates the biosynthesis of dolichol phosphate-mannose. Essential for the ER localization and stable expression of DPM1.
|
| Pathways
|
- Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
- N-Glycan biosynthesis
|
| Reactions
|
| Guanosine diphosphate mannose + Dolichol-20 → Guanosine diphosphate + Dolichyl phosphate D-mannose |
details
|
| UDP-N-acetyl-D-glucosamine + 1-Phosphatidyl-D-myo-inositol → UDP + |
details
|
|
| GO Classification
|
| Biological Process |
| dolichol-linked oligosaccharide biosynthetic process |
| protein N-linked glycosylation via asparagine |
| C-terminal protein lipidation |
| protein O-linked mannosylation |
| preassembly of GPI anchor in ER membrane |
| regulation of protein stability |
| Cellular Component |
| endoplasmic reticulum membrane |
| integral to endoplasmic reticulum membrane |
| dolichol-phosphate-mannose synthase complex |
| glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| Not Available |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| O94777 |
| UniProtKB/Swiss-Prot Entry Name
| Not Available |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| HGNC:3006 |
| References |
|---|
| General References
| Not Available |
