| Identification |
|---|
| HMDB Protein ID
| HMDBP11568 |
| Secondary Accession Numbers
| |
| Name
| Ig lambda-1 chain C regions |
| Synonyms
|
Not Available
|
| Gene Name
| IGLC1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in antigen binding |
| Specific Function
| Not Available |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 22q11.2 |
| SNPs
| IGLC1 |
| Gene Sequence
|
>320 bp
GTCAGCCCAAGGCCAACCCCACTGTCACTCTGTTCCCGCCCTCCTCTGAGGAGCTCCAAG
CCAACAAGGCCACACTAGTGTGTCTGATCAGTGACTTCTACCCGGGAGCTGTGACAGTGG
CCTGGAAGGCAGATGGCAGCCCCGTCAAGGCGGGAGTGGAGACCACCAAACCCTCCAAAC
AGAGCAACAACAAGTACGCGGCCAGCAGCTACCTGAGCCTGACGCCCGAGCAGTGGAAGT
CCCACAGAAGCTACAGCTGCCAGGTCACGCATGAAGGGAGCACCGTGGAGAAGACAGTGG
CCCCTACAGAATGTTCATAG
|
| Protein Properties |
|---|
| Number of Residues
| 106 |
| Molecular Weight
| 11347.6 |
| Theoretical pI
| 8.05 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ig lambda-1 chain C regions
GQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGVETTKPSK
QSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS
|
| External Links |
|---|
| GenBank ID Protein
| 1335154 |
| UniProtKB/Swiss-Prot ID
| P0CG04 |
| UniProtKB/Swiss-Prot Entry Name
| LAC1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| X51755 |
| GeneCard ID
| IGLC1 |
| GenAtlas ID
| IGLC1 |
| HGNC ID
| HGNC:5855 |
| References |
|---|
| General References
| - Fett JW, Deutsch HF: Primary structure of the Mcg lambda chain. Biochemistry. 1974 Sep 24;13(20):4102-14. [PubMed:4415202 ]
- Ely KR, Herron JN, Harker M, Edmundson AB: Three-dimensional structure of a light chain dimer crystallized in water. Conformational flexibility of a molecule in two crystal forms. J Mol Biol. 1989 Dec 5;210(3):601-15. [PubMed:2515285 ]
- Vasicek TJ, Leder P: Structure and expression of the human immunoglobulin lambda genes. J Exp Med. 1990 Aug 1;172(2):609-20. [PubMed:2115572 ]
- Hieter PA, Hollis GF, Korsmeyer SJ, Waldmann TA, Leder P: Clustered arrangement of immunoglobulin lambda constant region genes in man. Nature. 1981 Dec 10;294(5841):536-40. [PubMed:6273747 ]
|
