Human Metabolome Database: Showing Protein Zinc finger protein 219 (HMDBP10930)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 metabolite

Identification

HMDB Protein ID

HMDBP10930

Secondary Accession Numbers

17235

Name

Zinc finger protein 219

Synonyms

Not Available

Gene Name

ZNF219

Protein Type

Unknown

Biological Properties

General Function

Involved in histamine receptor activity

Specific Function

May be involved in transcriptional regulation

Pathways

Not Available

Reactions

Not Available

GO Classification

Component
intracellular
integral to membrane
cell part
intrinsic to membrane
membrane part
Function
transmembrane receptor activity
histamine receptor activity
g-protein coupled amine receptor activity
g-protein coupled receptor activity
ion binding
receptor activity
nucleic acid binding
signal transducer activity
molecular transducer activity
zinc ion binding
transition metal ion binding
binding
metal ion binding
cation binding
Process
signaling
signaling pathway
cell surface receptor linked signaling pathway
g-protein coupled receptor protein signaling pathway

Cellular Location

Nucleus

Gene Properties

Chromosome Location

Chromosome:1

Locus

14q11

SNPs

ZNF219

Gene Sequence

>2169 bp
ATGGAGGGCTCACGTCCCCGCGCCCCGAGCGGCCACTTAGCGCCGTCGCCGCCGGCTTTC
GACGGCGAGCTGGATCTGCAGCGATACTCCAACGGGCCAGCCGTGAGCGCAGGGTCGCTC
GGGATGGGAGCGGTGAGCTGGTCTGAGAGTCGTGCAGGCGAACGGCGCTTCCCCTGCCCT
GTATGCGGGAAGCGCTTCCGCTTCAACTCTATCCTTGCTTTGCACCTGCGGGCGCACCCA
GGAGCCCAGGCCTTCCAGTGCCCTCACTGCGGCCACCGCGCGGCGCAGCGGGCTCTGCTG
CGCTCGCACCTGCGCACACACCAGCCCGAGCGCCCACGTAGTCCTGCTGCACGCCTGTTG
CTGGAGTTGGAAGAGCGCGCGCTACTACGCGAGGCCCGACTGGGGAGAGCCCGAAGCTCA
GGGGGCATGCAGGCCACCCCTGCCACTGAGGGTCTGGCGCGGCCCCAGGCTCCTTCATCG
TCCGCCTTCCGTTGCCCCTACTGCAAAGGCAAGTTTCGCACCTCGGCGGAGCGCGAACGC
CACCTGCACATCCTGCATAGGCCCTGGAAGTGCGGCCTGTGCAGTTTCGGCTCCAGCCAG
GAGGAGGAGCTGCTGCACCACAGCCTGACGGCCCACGGGGCTCCCGAGCGTCCCCTGGCG
GCCACCTCCGCTGCGCCTCCGCCTCAGCCTCAGCCTCAGCCTCCACCCCAGCCCGAACCC
AGATCAGTCCCCCAGCCGGAGCCGGAGCCGGAGCCCGAACGTGAGGCAACCCCGACCCCA
GCTCCTGCCGCTCCCGAGGAGCCCCCAGCGCCTCCGGAGTTCCGCTGCCAAGTGTGCGGC
CAGAGCTTTACACAGTCTTGGTTTCTCAAGGGCCACATGCGTAAGCACAAGGCCTCCTTC
GATCATGCGTGTCCGGTGTGCGGCCGCTGCTTCAAGGAGCCCTGGTTCCTTAAGAACCAC
ATGAAGGTGCACGCCAGCAAGCTGGGCCCACTGCGTGCCCCGGGGCCTGCCTCCGGGCCT
GCCCGCGCCCCCCAGCCTCCTGACCTCGGCCTGCTGGCCTATGAGCCGTTGGGCCCAGCG
CTCCTCTTGGCCCCGGCTCCCACCCCGGCCGAGCGCCGTGAGCCCCCGAGCCTCTTGGGC
TACCTGAGCCTGCGAGCTGGCGAGGGCCGGCCCAACGGCGAGGGTGCTGAGCCCGGTCCC
GGCCGCAGCTTCGGAGGCTTCCGCCCGCTGTCCTCTGCTCTCCCGGCCCGGGCTCGCCGG
CACCGTGCGGAGGAGCCTGAGGAAGAAGAGGAGGTGGTGGAGGCCCAGGAGGAAACCTGG
GCCCGGGGCAGGTCGCTGGGCTCTCTGGCTTCCCTGCACCCGCGCCCGGGTGAGGGACCG
GGGCACTCTGCCTCTGCTGCTGGGGCCCAGGCAAGATCGACCGCCACGCAGGAAGAGAAT
GGGCTGTTGGTTGGAGGGACCCGGCCTGAAGGGGGCCGGGGCGCCACCGGCAAGGATTGT
CCTTTCTGCGGAAAATCTTTCCGCTCAGCACATCACCTCAAAGTGCATCTGCGAGTGCAC
ACAGGCGAGCGGCCCTACAAGTGTCCGCACTGCGACTACGCGGGCACCCAGTCCGGCTCG
CTCAAGTATCACCTACAGCGCCACCACCGGGAGCAGAGGAGCGGGGCCGGCCCCGGGCCA
CCCCCGGAGCCACCGCCTCCTTCCCAGCGGGGTTCGGCCCCGCAATCTGGAGCCAAGCCG
TCTCCGCAGCCTGCGACCTGGGTGGAGGGCGCCTCAAGTCCCCGGCCTCCTTCTAGCGGT
GCTGGGCCGGGGTCCCGTCGGAAGCCCGCCAGCCCTGGGAGGACCCTGCGCAACGGGCGA
GGCGGTGAGGCCGAACCCCTGGACCTGTCCTTGCGGGCAGGGCCGGGAGGCGAGGCCGGG
CCTGGGGGTGCCCTCCACCGCTGCCTCTTCTGCCCGTTCGCCACTGGAGCCCCAGAGCTC
ATGGCCTTGCACCTTCAAGTGCACCACAGCCGCCGGGCTAGGGGCCGCCGGCCACCCCAG
GCTGACGCGTCCCCGCCCTATGCCCGAGTACCATCAGGAGAGACCCCTCCCAGTCCTTCG
CAGGAAGGGGAGGAGGGCTCCGGGCTGTCCAGACCCGGAGAGGCAGGGCTGGGGGGGCAA
GAACGGTAG

Protein Properties

Number of Residues

722

Molecular Weight

76876.5

Theoretical pI

9.75

Pfam Domain Function

zf-C2H2 (PF00096 )

Signals

None

Transmembrane Regions

None

Protein Sequence

>Zinc finger protein 219
MEGSRPRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP
VCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLL
LELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERER
HLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEP
RSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASF
DHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPA
LLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARR
HRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEEN
GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGS
LKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSG
AGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPEL
MALHLQVHHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSGLSRPGEAGLGGQ
ER

External Links

GenBank ID Protein

6899807

UniProtKB/Swiss-Prot ID

Q9P2Y4

UniProtKB/Swiss-Prot Entry Name

ZN219_HUMAN

PDB IDs

Not Available

GenBank Gene ID

GeneCard ID

GenAtlas ID

HGNC ID

References

General References

Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell. 2006 Nov 3;127(3):635-48. [PubMed:17081983 ]
Sakai T, Toyoda A, Hashimoto K, Maeda H: Isolation and characterization of a novel zinc finger gene, ZNF219, and mapping to the human chromosome 14q11 region. DNA Res. 2000 Apr 28;7(2):137-41. [PubMed:10819330 ]