Human Metabolome Database: Showing Protein Putative uncharacterized protein VRK3 (HMDBP09479)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 metabolites

Identification

HMDB Protein ID

HMDBP09479

Secondary Accession Numbers

15370

Name

Putative uncharacterized protein VRK3

Synonyms

SubName: cDNA FLJ53256, highly similar to Homo sapiens vaccinia related kinase 3 (VRK3), transcript variant 2, mRNA

Gene Name

VRK3

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein kinase activity

Specific Function

Not Available

Pathways

Not Available

Reactions

Not Available

GO Classification

Function
catalytic activity
protein kinase activity
atp binding
adenyl ribonucleotide binding
adenyl nucleotide binding
purine nucleoside binding
nucleoside binding
kinase activity
transferase activity, transferring phosphorus-containing groups
transferase activity
binding
Process
metabolic process
cellular metabolic process
phosphorus metabolic process
phosphate metabolic process
phosphorylation
protein amino acid phosphorylation

Cellular Location

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

19q13

SNPs

VRK3

Gene Sequence

>1275 bp
ATGATCTCCTTCTGTCCAGACTGTGGCAAAAGTATCCAAGCGGCATTCAAATTCTGCCCC
TACTGTGGAAATTCTTTGCCTGTAGAGGAGCATGTAGGGTCCCAGACCTTTGTCAATCCA
CATGTGTCATCCTTCCAAGGCTCCGGGAGCAGACCCCCAACCCCCAAAAGCAGCCCTCAG
AAGACCAGGAAGAGCCCTCAGGTGACCAGGGGTAGCCCTCAGAAGACCAGCTGTAGCCCT
CAGAAGACCAGGCAGAGCCCTCAGACGCTGAAGCGGAGCCGAGTGACCACCTCACTTGAA
GCTTTGCCCACAGGGACAGTGCTGACAGACAAGAGTGGGCGACAGTGGAAGCTGAAGTCC
TTCCAGACCAGGGACAACCAGGGCATTCTCTATGAAGCTGCACCCACCTCCACCCTCACC
TGTGACTCAGGACCACAGAAGCAAAAGTTCTCACTCAAACTGGATGCCAAGGATGGGCGC
TTGTTCAATGAGCAGAACTTCTTCCAGCGGGCCGCCAAGCCTCTGCAAGTCAACAAGTGG
AAGAAGCTGTACTCGACCCCACTGCTGGCCATCCCTACCTGCATGGGTTTCGGTGTTCAC
CAGGACAAATACAGGTTCTTGGTGTTACCCAGCCTGGGGAGGAGCCTTCAGTCGGCCCTG
GATGTCAGCCCAAAGCATGTGCTGTCAGAGAGGTCTGTGCTGCAGGTGGCCTGCCGGCTG
CTGGATGCCCTGGAGTTCCTCCATGAGAATGAGTATGTTCATGGAAATGTGACAGCTGAA
AATATCTTTGTGGATCCAGAGGACCAGAGTCAGGTGACTTTGGCAGGCTATGGCTTCGCC
TTCCGCTATTGCCCAAGTGGCAAACACGTGGCCTACGTGGAAGGCAGCAGGAGCCCTCAC
GAGGGGGACCTTGAGTTCATTAGCATGGACCTGCACAAGGGATGCGGGCCCTCCCGCCGC
AGCGACCTCCAGAGCCTGGGCTACTGCATGCTGAAGTGGCTCTACGGGTTTCTGCCATGG
ACAAATTGCCTTCCCAACACTGAGGACATCATGAAGCAAAAACAGAAGTTTGTTGATAAG
CCGGGGCCCTTCGTGGGACCCTGCGGTCACTGGATCAGGCCCTCAGAGACCCTGCAGAAG
TACCTGAAGGTGGTGATGGCCCTCACGTATGAGGAGAAGCCGCCCTACGCCATGCTGAGG
AACAACCTAGAAGCTTTGCTGCAGGATCTGCGTGTGTCTCCATATGACCCCATTGGCCTC
CCGATGGTGCCCTAG

Protein Properties

Number of Residues

424

Molecular Weight

47501.1

Theoretical pI

9.31

Pfam Domain Function

Pkinase (PF00069 )

Signals

None

Transmembrane Regions

None

Protein Sequence

>Putative uncharacterized protein VRK3
MISFCPDCGKSIQAAFKFCPYCGNSLPVEEHVGSQTFVNPHVSSFQGSGSRPPTPKSSPQ
KTRKSPQVTRGSPQKTSCSPQKTRQSPQTLKRSRVTTSLEALPTGTVLTDKSGRQWKLKS
FQTRDNQGILYEAAPTSTLTCDSGPQKQKFSLKLDAKDGRLFNEQNFFQRAAKPLQVNKW
KKLYSTPLLAIPTCMGFGVHQDKYRFLVLPSLGRSLQSALDVSPKHVLSERSVLQVACRL
LDALEFLHENEYVHGNVTAENIFVDPEDQSQVTLAGYGFAFRYCPSGKHVAYVEGSRSPH
EGDLEFISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKFVDK
PGPFVGPCGHWIRPSETLQKYLKVVMALTYEEKPPYAMLRNNLEALLQDLRVSPYDPIGL
PMVP

External Links

GenBank ID Protein

71164888

UniProtKB/Swiss-Prot ID

Q8IV63

UniProtKB/Swiss-Prot Entry Name

A6NEG5_HUMAN

PDB IDs

Not Available

GenBank Gene ID

GeneCard ID

GenAtlas ID

HGNC ID

References

General References

Grimwood J, Gordon LA, Olsen A, Terry A, Schmutz J, Lamerdin J, Hellsten U, Goodstein D, Couronne O, Tran-Gyamfi M, Aerts A, Altherr M, Ashworth L, Bajorek E, Black S, Branscomb E, Caenepeel S, Carrano A, Caoile C, Chan YM, Christensen M, Cleland CA, Copeland A, Dalin E, Dehal P, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Garcia C, Georgescu AM, Glavina T, Gomez M, Gonzales E, Groza M, Hammon N, Hawkins T, Haydu L, Ho I, Huang W, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Larionov V, Leem SH, Lopez F, Lou Y, Lowry S, Malfatti S, Martinez D, McCready P, Medina C, Morgan J, Nelson K, Nolan M, Ovcharenko I, Pitluck S, Pollard M, Popkie AP, Predki P, Quan G, Ramirez L, Rash S, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, She X, Smith D, Slezak T, Solovyev V, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wagner M, Wheeler J, Wu K, Xie G, Yang J, Dubchak I, Furey TS, DeJong P, Dickson M, Gordon D, Eichler EE, Pennacchio LA, Richardson P, Stubbs L, Rokhsar DS, Myers RM, Rubin EM, Lucas SM: The DNA sequence and biology of human chromosome 19. Nature. 2004 Apr 1;428(6982):529-35. [PubMed:15057824 ]