Human Metabolome Database: Showing Protein PASK protein (HMDBP09465)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 metabolites

Identification

HMDB Protein ID

HMDBP09465

Secondary Accession Numbers

15353

Name

PASK protein

Synonyms

Not Available

Gene Name

PASK

Protein Type

Enzyme

Biological Properties

General Function

Involved in signal transducer activity

Specific Function

Not Available

Pathways

Not Available

Reactions

Not Available

GO Classification

Function
adenyl ribonucleotide binding
molecular transducer activity
signal transducer activity
protein kinase activity
atp binding
adenyl nucleotide binding
purine nucleoside binding
nucleoside binding
kinase activity
transferase activity, transferring phosphorus-containing groups
transferase activity
binding
catalytic activity
Process
protein amino acid phosphorylation
phosphorylation
phosphate metabolic process
phosphorus metabolic process
signal transduction
regulation of cellular process
cellular metabolic process
regulation of transcription, dna-dependent
regulation of transcription
regulation of gene expression
regulation of macromolecule metabolic process
regulation of metabolic process
regulation of biological process
biological regulation
metabolic process

Cellular Location

Not Available

Gene Properties

Chromosome Location

Chromosome:2

Locus

2q37.3

SNPs

PASK

Gene Sequence

>3432 bp
ATGGAGGACGGGGGCTTAACAGCCTTTGAAGAGGACCAGAGATGCCTTTCCCAGAGCCTC
CCCTTGCCAGTGTCAGCAGAGGGCCCAGCTGCACAGACCACTGCTGAGCCCAGCAGGTCG
TTTTCCTCAGCCCACAGACACCTGAGCAGAAGGAATGGGCTTTCCAGACTCTGCCAGAGC
AGGACGGCGCTCTCTGAAGACAGATGGAGCTCCTATTGTCTATCATCACTGGCTGCCCAG
AATATTTGTACAAGTAAACTGCACTGCCCTGCTGCCCCTGAGCACACGGACCCGTCCGAA
CCGCGGGGCAGTGTGTCCTGCTGCTCCCTGCTGCGGGGACTGTCCTCAGGGTGGTCCTCA
CCTCTGCTTCCGGCCCCTGTGTGCAACCCTAACAAGGCCATCTTCACGGTGGATGCCAAG
ACCACAGAGATCCTGGTTGCTAACGACAAAGCTTGCGGGCTCCTGGGGTACAGCAGCCAG
GACCTGATTGGCCAGAAGCTCACGCAGTTCTTTCTGAGGTCAGATTCTGATGTGGTGGAG
GCCCTCAGCGAGGAGCACATGGAGGCCGACGGCCACGCTGCGGTGGTGTTTGGCACGGTG
GTGGACATCATCAGCCGTAGTGGGGAGAAGATTCCAGTGTCTGTGTGGATGAAGAGGATG
CGGCAGGAGCGCCGCCTATGCTGCGTGGTGGTCCTGGAGCCCGTGGAGAGGGTCTCGACC
TGGGTCGCTTTCCAGAGCGATGGCACCATCACGTCATGTGACAGTCTCTTTGCTCATCTT
CACGGGTACGTGTCTGGGGAGGACGTGGCTGGGCAGCATATCACAGACCTGATCCCTTCT
GTGCAGCTCCCTCCTTCTGGCCAGCACATCCCAAAGAATCTCAAGATTCAGAGGTCTGTT
GGAAGAGCCAGGGACGGTACCACCTTCCCTCTGAGCTTAAAGCTGAAATCCCAACCCAGC
AGCGAGGAGGCGACCACCGGTGAGGCGGCCCCTGTGAGCGGCTACCGGGCATCTGTCTGG
GTGTTCTGCACCATCAGTGGCCTCATCACCCTCCTGCCGGATGGGACCATCCACGGCATC
AACCACAGCTTCGCGCTGACACTGTTTGGTTACGGAAAGACGGAGCTCCTGGGCAAGAAT
ATCACTTTCCTGATTCCTGGTTTCTACAGCTACATGGACCTTGCGTACAACAGCTCATTA
CAGCTCCCAGACCTGGCCAGCTGCCTGGACGTCGGCAATGAGAGTGGGTGTGGGGAGAGA
ACCTTGGACCCGTGGCAGGGCCAGGACCCAGCTGAGGGGGGCCAGGATCCAAGGATTAAT
GTCGTGCTTGCTGGTGGCCACGTTGTGCCCCGAGATGAGATCCGGAAGCTGATGGAAAGC
CAAGACATCTTCACCGGGACTCAGACTGAGCTGATTGCTGGAGGCCAGCTCCTTTCCTGC
CTCTCACCTCAGCCTGCTCCAGGGGTGGACAATGTCCCAGAAGGAAGCCTGCCAGTGCAC
GGTGAACAGGCGCTGCCCAAGGACCAGCAAATCACTGCCTTGGGGAGAGAGGAACCTGTG
GCAATAGAGAGCCCCGGACAGGATCTTCTGGGAGAAAGCAGGTCTGAACCAGTGGATGTG
AAGCCATTTGCTTCCTGCGAAGATTCTGAAGCTCCAGTCCCAGCTGAGGATGGGGGCAGT
GATGCTGGCATGTGTGGCCTGTGTCAGAAGGCCCAGCTAGAGCGGATGGGAGTCAGTGGT
CCCAGCGGTTCAGACCTTTGGGCTGGGGCTGCCGTGGCCAAGCCCCAGGCCAAGGGTCAG
CTGGCGGGGGGCAGCCTCCTGATGCACTGCCCTTGCTATGGGAGTGAATGGGGCTTGTGG
TGGCGAAGCCAGGACTTGGCCCCCAGCCCCTCTGGGATGGCAGGCCTCTCGTTTGGGACA
CCTACTCTAGATGAGCCGTGGCTGGGAGTGGAAAACGACCGAGAAGAGCTGCAGACCTGC
TTGATTAAGGAGCAGCTGTCCCAGTTGAGCCTTGCGGGAGCCCTGGATGTCCCCCACGCC
GAACTCGTTCCGACAGAGTGCCAGGCTGTCACCGCTCCTGTGTCGTCCTGCGATCTGGGA
GGCAGAGACCTGTGCGGTGGCTGCACGGGCAGCTCCTCAGCCTGCTATGCCTTGGCCACG
GACCTCCCTGGGGGCCTGGAAGCAGTGGAGGCCCAGGAGGTTGATGTGAATTCGTTTTCC
TGGAACCTCAAGGAACTCTTTTTCAGTGACCAGACAGACCAAACGTCATCAAATTGTTCC
TGTGCTACGTCTGAACTCAGAGAGACACCCTCTTCCTTGGCAGTGGGCTCCGATCCAGAT
GTAGGCAGTCTCCAGGAACAGGGGTCGTGTGTCCTGGATGACAGGGAGCTGTTACTACTG
ACCGGCACCTGTGTTGACCTTGGCCAAGGCCGACGGTTCCGGGAGAGCTGTGTGGGACAT
GATCCAACAGAACCGCTTGAGGTTTGTTTGGTGTCCTCTGAGCATTATGCAGCAAGCGAC
AGAGAAAGCCCAGGACACGTTCCTTCCACGTTGGATGCTGGCCCTGAGGACACGTGCCCA
TCAGCAGAGGAGCCAAGGCTGAACGTCCAGGTCACCTCCACGCCCGTGATCGTGATGCGC
GGGGCTGCTGGCCTGCAGCGGGAGATCCAGGAGGGTGCCTACTCCGGGAGCTGCTACCAT
CGAGATGGCTTACGGCTGAGTATACAGTTTGAGGTGAGGCGGGTGGAGCTCCAGGGCCCC
ACACCTCTGTTCTGCTGCTGGCTGGTGAAAGACCTCCTCCACAGCCAACGCGACTCAGCC
GCCAGGACCCGCCTGTTCCTTGCCAGCCTGCCCGGCTCCACCCACTCTACCGCTGCTGAG
CTCACCGGACCCAGCCTGGTGGAAGTGCTCAGAGCCAGACCCTGGTTTGAGGAGCCCCCC
AAGGCTGTGGAACTGGAGGGGTTGGCGGCCTGTGAGGGCGAGTACTCCCAAAAGTACAGT
ACCATGAGCCCGCTGGGCAGTGGGGCCTTCGGCTTCGTGTGGACTGCTGTGGACAAGGAA
AAAAACAAGGAGGTGGTGGTGAAGTTTATTAAGAAGGAGAAGGTCTTGGAGGATTGTTGG
ATTGAGGATCCCAAACTTGGGAAAGTTACTTTAGAGATCGCAATTCTATCCAGGGTGGAG
CATTCCAATATCATCAAGGTATTGGATATATTTGAAAACCAAGGGTTCTTCCAGCTTGTG
ATGGAGAAGCACGGCTCCGGCCTAGACCTCTTCGCTTTCATCGACCGCCACCCCAGGCTG
GATGAGCCCCTGGCGAGCTACATCTTCCGACAAGTGAGAGCAGGCCAGAGCCGTGTTAGT
GTGAACGCAGGCCTGGGTGCCTGGGTCCGGTGGCTGCAAAGATCAGTGATCCATACTCGG
TTCTCTCTCTGA

Protein Properties

Number of Residues

1143

Molecular Weight

123076.4

Theoretical pI

4.65

Pfam Domain Function

PAS (PF00989 )
Pkinase (PF00069 )

Signals

None

Transmembrane Regions

None

Protein Sequence

>PASK protein
MEDGGLTAFEEDQRCLSQSLPLPVSAEGPAAQTTAEPSRSFSSAHRHLSRRNGLSRLCQS
RTALSEDRWSSYCLSSLAAQNICTSKLHCPAAPEHTDPSEPRGSVSCCSLLRGLSSGWSS
PLLPAPVCNPNKAIFTVDAKTTEILVANDKACGLLGYSSQDLIGQKLTQFFLRSDSDVVE
ALSEEHMEADGHAAVVFGTVVDIISRSGEKIPVSVWMKRMRQERRLCCVVVLEPVERVST
WVAFQSDGTITSCDSLFAHLHGYVSGEDVAGQHITDLIPSVQLPPSGQHIPKNLKIQRSV
GRARDGTTFPLSLKLKSQPSSEEATTGEAAPVSGYRASVWVFCTISGLITLLPDGTIHGI
NHSFALTLFGYGKTELLGKNITFLIPGFYSYMDLAYNSSLQLPDLASCLDVGNESGCGER
TLDPWQGQDPAEGGQDPRINVVLAGGHVVPRDEIRKLMESQDIFTGTQTELIAGGQLLSC
LSPQPAPGVDNVPEGSLPVHGEQALPKDQQITALGREEPVAIESPGQDLLGESRSEPVDV
KPFASCEDSEAPVPAEDGGSDAGMCGLCQKAQLERMGVSGPSGSDLWAGAAVAKPQAKGQ
LAGGSLLMHCPCYGSEWGLWWRSQDLAPSPSGMAGLSFGTPTLDEPWLGVENDREELQTC
LIKEQLSQLSLAGALDVPHAELVPTECQAVTAPVSSCDLGGRDLCGGCTGSSSACYALAT
DLPGGLEAVEAQEVDVNSFSWNLKELFFSDQTDQTSSNCSCATSELRETPSSLAVGSDPD
VGSLQEQGSCVLDDRELLLLTGTCVDLGQGRRFRESCVGHDPTEPLEVCLVSSEHYAASD
RESPGHVPSTLDAGPEDTCPSAEEPRLNVQVTSTPVIVMRGAAGLQREIQEGAYSGSCYH
RDGLRLSIQFEVRRVELQGPTPLFCCWLVKDLLHSQRDSAARTRLFLASLPGSTHSTAAE
LTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPLGSGAFGFVWTAVDKE
KNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHSNIIKVLDIFENQGFFQLV
MEKHGSGLDLFAFIDRHPRLDEPLASYIFRQVRAGQSRVSVNAGLGAWVRWLQRSVIHTR
FSL

External Links

GenBank ID Protein

116283959

UniProtKB/Swiss-Prot ID

Q96RG2

UniProtKB/Swiss-Prot Entry Name

Q05BE4_HUMAN

PDB IDs

1LL8

GenBank Gene ID

GeneCard ID

GenAtlas ID

HGNC ID

References

General References

Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]