Human Metabolome Database: Showing Protein EPH receptor A8 (HMDBP09444)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 metabolites

Identification

HMDB Protein ID

HMDBP09444

Secondary Accession Numbers

15325

Name

EPH receptor A8

Synonyms

Not Available

Gene Name

EPHA8

Protein Type

Enzyme

Biological Properties

General Function

Involved in ephrin receptor activity

Specific Function

Not Available

Pathways

Not Available

Reactions

Not Available

GO Classification

Component
integral to plasma membrane
integral to membrane
intrinsic to membrane
membrane part
membrane
cell part
Function
ephrin receptor activity
binding
transmembrane receptor protein tyrosine kinase activity
protein tyrosine kinase activity
protein kinase activity
protein binding
catalytic activity
adenyl ribonucleotide binding
adenyl nucleotide binding
purine nucleoside binding
nucleoside binding
transferase activity
atp binding
transferase activity, transferring phosphorus-containing groups
kinase activity
Process
cell surface receptor linked signaling pathway
metabolic process
transmembrane receptor protein tyrosine kinase signaling pathway
enzyme linked receptor protein signaling pathway
protein amino acid phosphorylation
phosphorylation
signaling pathway
signaling
phosphate metabolic process
phosphorus metabolic process
cellular metabolic process

Cellular Location

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

1p36.12

SNPs

EPHA8

Gene Sequence

>1488 bp
ATGGCCCCCGCCCGGGGCCGCCTGCCCCCTGCGCTCTGGGTCGTCACGGCCGCGGCGGCG
GCGGCCACCTGCGTGTCCGCGGCGCGCGGCGAAGTGAATTTGCTGGACACGTCGACCATC
CACGGGGACTGGGGCTGGCTCACGTATCCGGCTCATGGGTGGGACTCCATCAACGAGGTG
GACGAGTCCTTCCAGCCCATCCACACGTACCAGGTTTGCAACGTCATGAGCCCCAACCAG
AACAACTGGCTGCGCACGAGCTGGGTCCCCCGAGACGGCGCCCGGCGCGTCTATGCTGAG
ATCAAGTTTACCCTGCGCGACTGCAACAGCATGCCTGGTGTGCTGGGCACCTGCAAGGAG
ACCTTCAACCTCTACTACCTGGAGTCGGACCGCGACCTGGGGGCCAGCACACAAGAAAGC
CAGTTCCTCAAAATCGACACCATTGCGGCCGACGAGAGCTTCACAGGTGCCGACCTTGGT
GTGCGGCGTCTCAAGCTCAACACGGAGGTGCGCAGTGTGGGTCCCCTCAGCAAGCGCGGC
TTCTACCTGGCCTTCCAGGACATAGGTGCCTGCCTGGCCATCCTCTCTCTCCGCATCTAC
TATAAGAAGTGCCCTGCCATGGTGCGCAATCTGGCTGCCTTCTCGGAGGCAGTGACGGGG
GCCGACTCGTCCTCACTGGTGGAGGTGAGGGGCCAGTGCGTGCGGCACTCAGAGGAGCGG
GACACACCCAAGATGTACTGCAGCGCGGAGGGCGAGTGGCTCGTGCCCATCGGCAAATGC
GTGTGCAGTGCCGGCTACGAGGAGCGGCGGGATGCCTGTGTGGCCTGTGAGCTGGGCTTC
TACAAGTCAGCCCCTGGGGACCAGCTGTGTGCCCGCTGCCCTCCCCACAGCCACTCCGCA
GCTCCAGCCGCCCAAGCCTGCCACTGTGACCTCAGCTACTACCGTGCAGCCCTGGACCCG
CCGTCCTCAGCCTGCACCCGGCCACCCTCGGCACCAGTGAACCTGATCTCCAGTGTGAAT
GGGACATCAGTGACTCTGGAGTGGGCCCCTCCCCTGGACCCAGGTGGCCGCAGTGACATC
ACCTACAATGCCGTGTGCCGCCGCTGCCCCTGGGCACTGAGCCGCTGCGAGGCATGTGGG
AGCGGCACCCGCTTTGTGCCCCAGCAGACAAGCCTGGTGCAGGCCAGCCTGCTGGTGGCC
AACCTGCTGGCCCACATGAACTACTCCTTCTGGATCGAGGCCGTCAATGGCGTGTCCGAC
CTGAGCCCCGAGCCCCGCCGGGCCGCTGTGGTCAACATCACCACGAACCAGGCAGGTAGG
CGGAGAAACTCCGTCCCGCAGCGTCCTGGTCCCCCAGCTTCCCCTGCCTCAGACCCATCC
AGGGATCAGAGCTCTGCCGGGGACGTGCTGTGGGCCTTTAGGCAAGTGCCTCTCTGGCCC
TGCGCTCCTCACCAGGACCCAGAGCTGGAGGCTCTTCATTGCCTTTAG

Protein Properties

Number of Residues

495

Molecular Weight

53899.3

Theoretical pI

6.79

Pfam Domain Function

Ephrin_lbd (PF01404 )
fn3 (PF00041 )

Signals

None

Transmembrane Regions

None

Protein Sequence

>EPH receptor A8
MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV
DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE
TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG
FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER
DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA
APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI
TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD
LSPEPRRAAVVNITTNQAGRRRNSVPQRPGPPASPASDPSRDQSSAGDVLWAFRQVPLWP
CAPHQDPELEALHCL

External Links

GenBank ID Protein

56417854

UniProtKB/Swiss-Prot ID

P29322

UniProtKB/Swiss-Prot Entry Name

Q8IUX6_HUMAN

PDB IDs

Not Available

GenBank Gene ID

GeneCard ID

GenAtlas ID

HGNC ID

References

General References

Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]