Human Metabolome Database: Showing Protein Probable E3 ubiquitin-protein ligase MYCBP2 (HMDBP09272)

Identification Biological properties Gene properties Protein properties External links References XML Show 4 metabolites

Identification

HMDB Protein ID

HMDBP09272

Secondary Accession Numbers

15100

Name

Probable E3 ubiquitin-protein ligase MYCBP2

Synonyms

Myc-binding protein 2
Pam/highwire/rpm-1 protein
Protein associated with Myc

Gene Name

MYCBP2

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein binding

Specific Function

Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. May function as a facilitator or regulator of transcriptional activation by MYC. May have a role during synaptogenesis

Pathways

Not Available

Reactions

Not Available

GO Classification

Component
macromolecular complex
anaphase-promoting complex
nuclear ubiquitin ligase complex
ubiquitin ligase complex
protein complex
Function
zinc ion binding
protein binding
ion binding
transition metal ion binding
binding
metal ion binding
cation binding
Process
biological regulation
regulation of biological process
regulation of cellular process
regulation of cell cycle
regulation of mitotic cell cycle
regulation of mitosis
regulation of mitotic metaphase/anaphase transition

Cellular Location

Nucleus

Gene Properties

Chromosome Location

Chromosome:1

Locus

13q22

SNPs

MYCBP2

Gene Sequence

>14037 bp
ATGATGATGTGCGCAGCGACTGCCTCCCCCGCCGCCGCCTCCTCGGGGCTCGGCGGGGAC
GGATTCTACCCAGCCGCCACCTTCTCTTCCTCCCCGGCGCCGGGGGCGCTGTTCATGCCG
GTTCCCGACGGCTCCGTGGCTGCTGCGGGGCTGGGGCTGGGGCTACCCGCCGCGGACTCC
CGGGGTCACTACCAGCTGCTGCTGTCAGGCCGGGCCCTGGCCGACCGCTACCGGAGGATT
TATACCGCTGCGCTCAATGACAGGGACCAGGGGGGCGGCAGCGCTGGACACCCAGCCTCC
AGGAATAAGAAAATTTTAAATAAGAAGAAATTGAAAAGAAAACAGAAGAGCAAATCAAAA
GTGAAGACAAGAAGCAAGTCTGAAAACTTAGAGAATACAGTAATCATACCAGATATCAAA
CTACATAGCAATCCTTCTGCTTTCAATATTTACTGTAATGTACGCCATTGCGTTCTGGAA
TGGCAGAAAAAGGAAATATCATTGGCAGCCGCATCTAAGAACTCTGTGCAGAGTGGAGAA
TCAGATAGTGATGAAGAAGAGGAATCCAAAGAGCCCCCTATCAAGCTTCCAAAGATTATT
GAGGTTGGCCTTTGTGAAGTTTTTGAATTGATCAAAGAGACACGATTTTCTCATCCATCC
CTGTGTCTCAGGAGTCTCCAAGCCCTGCTCAACGTGCTGCAGGGCCAGCAGCCAGAAGGC
CTCCAGTCTGAGCCACCTGAGGTCCTAGAGTCTCTCTTCCAGCTTCTTTTGGAAATCACC
GTTCGAAGTACTGGGATGAATGACAGCACAGGACAGTCCTTAACAGCACTTTCCTGTGCT
TGCCTCTTTAGTCTGGTGGCTTCTTGGGGAGAAACAGGAAGGACACTTCAGGCCATCTCT
GCTATCCTCACCAACAATGGAAGCCATGCTTGCCAAACTATTCAGGTGCCAACAATTCTA
AATTCGCTACAGAGAAGTGTACAAGCAGTTTTGGTGGGAAAAATTCAAATTCAGGACTGG
TTTAGTAATGGCATTAAGAAAGCAGCTTTAATGCACAAGTGGCCATTAAAAGAAATATCT
GTTGATGAAGATGACCAATGTCTACTTCAGAATGATGGATTTTTTCTTTATCTATTATGC
AAGGATGGATTATATAAAATAGGCTCTGGATACAGTGGAACAGTTAGGGGCCATATATAC
AATTCTACATCCCGTATTAGAAACAGAAAAGAAAAAAAGTCTTGGTTAGGGTATGCTCAG
GGTTATTTATTATATAGAGATGTGAATAACCACAGCATGACAGCCATAAGGATAAGCCCT
GAAACACTGGAGCAAGATGGTACTGTGATGTTACCAGATTGCCACACTGAAGGTCAAAAT
ATTTTATTCACTGATGGAGAATATATTAATCAGATAGCTGCTTCAAGAGATGATGGCTTT
GTTGTCAGAATATTTGCCACAAGCACTGAACCTGTTCTACAGCAAGAATTGCAACTTAAA
CTGGCTAGAAAATGCTTACATGCCTGTGGTATCTCACTATTCGATCTGGAAAAGGACTTG
CATATTATAAGTACAGGATTTGATGAGGAGTCAGCAATTCTTGGTGCAGGACGAGAGTTT
GCGCTAATGAAAACAGCAAATGGAAAGATATATTACACTGGCAAATACCAGAGTCTTGGA
ATCAAACAAGGTGGTCCTTCAGCAGGAAAATGGGTTGAGCTACCAATTACAAAATCTCCA
AAGATAGTACACTTCTCAGTTGGACACGATGGCTCTCACGCCCTTTTAGTTGCAGAAGAT
GGGAGCATATTCTTTACAGGATCTGCTAGTAAAGGAGAAGATGGAGAATCAACTAAGAGC
AGACGGCAATCCAAACCTTATAAACCTAAAAAGATAATTAAGATGGAAGGAAAGATTGTG
GTATATACAGCCTGCAATAATGGAAGTAGTTCTGTTATTTCTAAAGATGGAGAACTCTAC
ATGTTTGGAAAAGATGCCATTTACTCTGATAGTTCAAGTTTGGTAACTGATTTGAAGGGC
CATTTTGTAACTCAGGTAGCTATGGGCAAAGCTCACACTTGTGTTTTAATGAAGAATGGA
GAGGTGTGGACATTTGGTGTAAATAATAAAGGACAGTGTGGACGAGATACTGGTGCCATG
AACCAAGGTGGGAAAGGGTTTGGAGTTGAAAATATGGCAACAGCAATGGATGAAGACCTG
GAAGAAGAACTAGATGAAAAAGATGAGAAGTCTATGATGTGCCCTCCAGGCATGCACAAA
TGGAAGCTGGAGCAGTGCATGGTTTGCACTGTCTGTGGAGACTGTACAGGTTATGGAGCC
AGCTGTGTCAGTAGTGGACGGCCAGACAGAGTCCCCGGAGGGATCTGTGGTTGTGGTTCC
GGAGAATCTGGTTGTGCTGTGTGTGGATGTTGCAAGGCCTGTGCAAGAGAGTTAGATGGT
CAAGAGGCAAGACAAAGAGGAATTCTTGATGCAGTGAAAGAAATGATACCTTTAGATCTT
CTTTTAGCTGTCCCAGTGCCCGGGGTTAACATTGAAGAACACCTTCAGTTACGACAAGAA
GAAAAACGGCAACGTGTAATCAGAAGGCACAGATTAGAGGAAGGAAGAGGCCCCCTTGTA
TTTGCTGGTCCTATTTTTATGAACCATCGAGAACAGGCTCTAGCCAGACTCAGATCCCAT
CCAGCACAGCTAAAGCATAAACGGGACAAGCACAAAGATGGAAGTGGAGAAAGAGGCGAA
AAGGATGCAAGCAAAATCACAACATACCCTCCAGGCTCTGTGCGATTTGACTGTGAGCTC
CGGGCAGTCCAAGTCAGCTGTGGATTTCACCATTCAGTGGTTTTAATGGAAAATGGAGAT
GTCTATACATTTGGTTATGGGCAGCATGGGCAGCTAGGACATGGAGATGTCAACTCCAGG
GGATGTCCCACTCTTGTTCAAGCATTGCCAGGCCCTAGCACACAAGTCACTGCAGGCAGC
AACCATACGGCAGTACTTTTAATGGATGGACAGGTCTTCACATTTGGAAGTTTTTCTAAA
GGACAACTGGGCAGACCAATTTTGGATGTGCCATATTGGAATGCAAAGCCAGCTCCCATG
CCTAACATTGGATCAAAATATGGAAGAAAAGCTACTTGGATAGGTGCAAGTGGGGACCAA
ACTTTTTTACGAATTGATGAAGCACTTATTAATTCTCATGTACTTGCTACATCAGAAATT
TTTGCCAGTAAACACATAATAGGCTTGGTACCTGCTTCTATATCAGAACCTCCTCCATTT
AAATGCCTTCTGATAAATAAAGTGGATGGGAGTTGTAAAACTTTTAATGACTCAGAACAA
GAGGATCTGCAAGGATTTGGTGTGTGTCTTGATCCTGTATATGATGTAATTTGGAGGTTT
CGACCAAATACTAGAGAGCTGTGGTGTTACAATGCGGTGGTTGCTGATGCCAGGCTTCCC
TCTGCAGCAGACATGCAGTCCAGATGTAGTATCCTAAGTCCTGAACTTGCCTTACCAACA
GGATCAAGGGCCCTCACTACCCGATCTCATGCAGCTTTGCACATTTTAGGTTGTCTTGAT
ACCTTGGCAGCTATGCAGGACTTAAAAATGGGTGTTGCAAGTACAGAGGAAGAGACTCAA
GCAGTAATGAAGGTTTATTCTAAAGAAGATTATAGTGTGGTAAACAGGTTTGAAAGTCAT
GGAGGAGGCTGGGGTTATTCTGCCCATTCAGTAGAAGCTATACGTTTCAGTGCCGACACT
GATATTTTACTTGGTGGTCTTGGTCTGTTTGGAGGTAGAGGAGAATATACTGCTAAAATT
AAGCTGTTTGAATTGGGTCCTGATGGAGGAGATCATGAAACTGATGGTGACCTTCTTGCA
GAGACTGATGTATTGGCTTATGACTGTGCTGCTAGAGAAAAATATGCAATGATGTTTGAT
GAGCCTGTTCTCCTGCAAGCTGGGTGGTGGTATGTGGCATGGGCCCGAGTGTCAGGACCC
AGCAGTGACTGTGGATCTCATGGACAGGCATCTATTACCACAGATGATGGGGTTGTTTTC
CAGTTCAAGAGTTCAAAGAAATCAAATAATGGTACAGATGTTAATGCGGGTCAGATACCT
CAGTTATTATACAGACTTCCAACCAGTGATGGCAGTGCTTCAAAAGGCAAACAGCAAACC
AGTGAACCTGTACACATTTTAAAGAGGTCTTTTGCAAGAACTGTCTCAGTGGAATGTTTT
GAGTCATTGTTGAGTATTCTTCACTGGAGCTGGACCACCTTAGTCTTAGGAGTTGAAGAA
CTTAGAGGATTAAAAGGATTCCAGTTCACAGCTACACTCCTAGATTTAGAGAGACTGCGC
TTTGTGGGTACCTGTTGTCTGAGGTTATTGCGTGTCTATACCTGTGAAATTTACCCAGTG
TCAGCTACAGGAAAAGCAGTTGTAGAAGAAACTAGCAAATTAGCAGAGTGTATTGGAAAA
ACCAGAACTTTGTTAAGAAAAATTTTATCAGAAGGAGTTGATCACTGCATGGTGAAATTG
GATAATGATCCTCAAGGATATCTCAGTCAACCCTTGAGTCTTCTAGAAGCTGTCCTTCAG
GAATGTCATAATACTTTCACTGCCTGCTTTCATTCTTTCTACCCAACTCCTGCCTTACAG
TGGGCTTGCCTTTGTGATCTGCTGAATTGTTTGGATCAGGATATCCAAGAAGCAAACTTC
AAGACATCAAGTAGCCGACTCCTTGCAGCTGTTATGTCAGCTCTGTGTCACACGTCTGTT
AAGCTGACTTCCATCTTCCCGATTGCGTATGATGGAGAAGTATTACTACGATCAATTGTT
AAACAAGTTAGTACAGAGAACGACTCAACACTAGTTCATCGTTTTCCCCTTTTGGTGGCA
CATATGGAAAAACTCAGCCAGAGTGAAGAGAATATCTCAGGGATGACAAGCTTCCGTGAA
GTTCTGGAGAAAATGCTGGTCATTGTTGTGCTACCAGTCAGGAACAGCCTGAGGAGAGAA
AATGAACTCTTCTCCTCCCACCTCGTCTCTAACACCTGTGGATTACTGGCCAGCATTGTC
AGTGAACTGACAGCGTCAGCCCTGGGATCTGAGGTTGATGGACTTAATTCTCTTCACTCT
GTAAAAGCTAGTGCTAACCGATTTACAAAAACAAGTCAGGGCAGAAGTTGGAACACTGGG
AACGGGTCCCCTGATGCAATCTGTTTTTCAGTAGACAAACCTGGAATAGTTGTGGTTGGT
TTCTCTGTCTATGGAGGAGGTGGAATTCATGAATATGAATTAGAGGTGTTGGTTGATGAT
AGTGAACATGCAGGAGATTCAACTCATTCCCACAGATGGACATCTCTGGAATTAGTGAAA
GGAACGTACACAACGGATGACTCACCCAGTGATATAGCTGAGATCAGACTTGACAAAGTG
GTTCCTTTAAAGGAAAATGTTAAATATGCTGTGCGCTTGAGGAACTATGGAAGCCGTACA
GCCAATGGAGATGGAGGAATGACCACAGTTCAGTGCCCTGATGGTGTGACATTCACATTC
AGCACGTGCAGCTTGAGCAGTAACGGCACAAACCAAACCAGAGGACAGATCCCACAGATA
CTCTACTATAGGAGTGAATTTGATGGAGATTTACAATCCCAACTTCTGAGTAAAGCCAAT
GAAGAAGATAAAAACTGTAGCAGAGCATTGTCTGTTGTAAGCACTGTCGTTCGAGCCTCT
AAGGACCTCCTGCACAGAGCTCTTGCTGTGGATGCTGATGACATTCCAGAACTGCTGAGT
TCTTCCAGTCTGTTTTCCATGCTGCTCCCCCTTATTATAGCCTACATAGGACCAGTAGCT
GCTGCTATTCCCAAGGTGGCTGTAGAAGTCTTTGGCCTTGTCCAACAATTGCTTCCGTCA
GTTGCCATTTTGAATCAGAAGTATGCACCGCCTGCCTTCAACCCTAATCAGTCGACAGAT
AGCACCACAGGAAACCAGCCTGAACAGGGCCTCTCTGCTTGTACAACCTCCAGTCACTAT
GCTGTCATAGAGAGTGAGCACCCGTATAAACCTGCCTGTGTGATGCATTACAAGGTGACA
TTCCCAGAATGTGTGAGGTGGATGACAATCGAATTTGACCCTCAGTGTGGTACTGCACAG
TCAGAAGATGTCCTTCGTTTGTTGATTCCTGTCAGAACTGTTCAGAATTCAGGATATGGA
CCAAAATTGACATCTGTTCATGAAAATCTTAATTCATGGATAGAATTAAAGAAATTTTCA
GGATCCTCTGGGTGGCCTACTATGGTTTTGGTGTTGCCAGGAAATGAGGCCCTTTTTTCA
TTGGAGACTGCATCAGATTATGTGAAAGATGACAAAGCTTCTTTCTATGGTTTTAAGTGT
TTTGCAATTGGATATGAATTTAGCCCTGGACCTGATGAGGGAGTCATCCAATTGGAAAAA
GAATTAGCCAATCTTGGTGGGGTTTGTGCAGCAGCTCTGATGAAGAAGGACCTAGCACTT
CCTATTGGTAATGAATTAGAAGAAGACCTTGAAATTCTTGAGGAGGCTGCATTGCAGGTG
TGCAAAACCCATTCTGGAATTCTTGGAAAGGGTCTAGCTCTTTCTCATTCACCAACTATA
TTAGAAGCACTTGAGGGAAATTTACCACTCCAAATCCAAAGCAATGAACAGTCTTTTCTG
GATGATTTTATTGCCTGTGTCCCAGGATCAAGTGGTGGAAGGCTTGCAAGGTGGCTTCAG
CCAGATTCATATGCGGATCCTCAGAAAACATCTTTGATCCTGAATAAGGATGATATTCGT
TGTGGTTGGCCTACCACCATAACTGTTCAAACAAAAGACCAGTATGGGGATGTGGTACAT
GTTCCCAATATGAAGGTGGAAGTGAAAGCTGTCCCTGTTTCTCAGAAAAAAATGTCTTTA
CAACAAGATCAAGCAAAGAAACCTCAAAGGATTCCTGGCAGTCCTGCAGTAACAGCTGCA
TCTTCTAATACTGACATGACTTATGGAGGGCTGGCATCACCAAAGCTAGATGTTTCATAT
GAACCAATGATAGTGAAGGAAGCTCGATATATTGCCATAACAATGATGAAGGTTTATGAA
AATTATTCATTTGAAGAACTACGTTTTGCATCACCAACTCCTAAGAGACCCAGTGAGAAT
ATGCTGATCCGTGTCAATAATGATGGGACTTATTGTGCAAATTGGACTCCAGGGGCTATT
GGACTCTACACTCTTCATGTTACCATTGATGGCATTGAAATCGATGCTGGTCTGGAAGTA
AAAGTAAAAGACCCACCAAAAGGGATGATACCACCAGGAACTCAGTTGGTCAAACCAAAG
TCTGAACCTCAGCCTAATAAGGTTCGAAAATTTGTGGCCAAGGACAGTGCGGGGCTTCGC
ATCCGTAGCCACCCTTCCCTTCAGAGTGAGCAGATAGGCATAGTGAAAGTCAATGGAACT
ATCACTTTTATTGATGAGATCCATAATGATGATGGTGTGTGGCTGAGGCTGAATGATGAG
ACAATAAAGAAGTATGTCCCTAACATGAATGGTTACACTGAAGCCTGGTGCCTCTCTTTT
AATCAACATCTTGGCAAGAGTCTTCTGGTCCCTGTTGACGAATCTAAAACTAATACTGAT
GACTTTTTCAAAGACATAAACTCCTGCTGCCCACAGGAAGCAACAATGCAAGAACAAGAT
ATGCCATTCTTGCGAGGAGGGCCAGGCATGTACAAGGTAGTGAAGACGGGACCTTCAGGT
CACAACATCAGAAGCTGCCCTAACCTTAGAGGTATCCCAATTGGAATGTTAGTTCTGGGA
AACAAAGTCAAAGCAGTGGGAGAGGTAACCAATTCTGAAGGGACATGGGTGCAACTGGAT
CAGAACAGCATGGTAGAGTTCTGTGAGAGTGATGAAGGAGAGGCATGGTCCTTAGCTAGA
GACAGAGGCGGAAACCAGTACCTCCGACATGAAGATGAACAAGCTCTTCTGGATCAGAAT
TCTCAAACTCCTCCTCCAAGCCCTTTCTCAGTGCAAGCTTTTAATAAAGGGGCAAGTTGC
AGTGCCCAAGGATTTGATTATGGACTCGGAAATAGCAAAGGTGATCGAGGAAACATCTCA
ACATCTTCTAAACCAGCCTCTACATCAGGAAAATCAGAGCTGTCCTCTAAACACAGCAGA
TCGCTTAAACCTGATGGACGTATGAGCCGGACTACTGCTGATCAGAAGAAGCCAAGGGGC
ACAGAAAGTTTATCTGCTAGTGAATCCCTCATCTTAAAATCTGATGCTGCAAAGTTGAGG
TCAGATTCCCACAGTAGGTCATTATCCCCCAACCATAACACCTTGCAGACATTGAAATCT
GATGGGAGGATGCCTTCTAGCTCCAGAGCTGAATCCCCAGGACCAGGTTCTCGGTTGTCA
TCTCCTAAGCCAAAGACTCTCCCAGCCAATAGGTCTAGCCCATCGGGTGCTAGTTCTCCA
CGCTCCTCCTCACCACATGATAAAAATCTACCTCAAAAAAGTACTGCTCCTGTTAAGACA
AAGCTTGATCCTCCTCGGGAACGTTCTAAATCAGACTCTTACACACTTGATCCAGATACC
CTCCGCAAGAAGAAAATGCCCCTCACAGAACCTTTGAGAGGACGGTCAACGTCACCAAAA
CCAAAATCAGTACCAAAGGATTCTACAGATTCCCCTGGATCTGAAAATAGAGCTCCCTCT
CCCCATGTGGTACAGGAAAACCTCCACAGTGAGGTGGTCGAAGTCTGCACCTCAAGTACT
TTAAAAACAAATAGTCTAACAGACAGCACCTGCGATGACAGCAGTGAATTTAAGAGTGTG
GATGAAGGTTCAAATAAAGTTCATTTTAGCATTGGAAAAGCACCACTGAAAGATGAACAG
GAAATGAGAGCATCTCCCAAAATAAGTCGAAAATGTGCTAATAGACACACCAGGCCCAAA
AAAGAAAAATCGAGTTTTCTTTTCAAAGGAGATGGATCCAAGCCTTTAGAGCCAGCCAAG
CAAGCCATGTCTCCTTCTGTGGCCGAATGTGCCAGAGCTGTGTTTGCTTCCTTCCTCTGG
CATGAAGGCATAGTACATGATGCAATGGCTTGTTCTTCTTTCCTAAAGTTTCATCCTGAA
CTTTCCAAAGAACATGCTCCTATAAGGAGTAGTTTAAATAGCCAACAACCTACAGAGGAA
AAAGAAACCAAGTTAAAAAATAGACATTCATTAGAAATATCATCTGCACTGAATATGTTT
AATATTGCACCCCATGGACCAGATATATCTAAGATGGGTAGCATCAACAAAAACAAGGTA
TTGTCTATGCTTAAGGAACCACCTCTGCATGAAAAATGTGAGGATGGGAAAACCGAGACC
ACTTTTGAAATGTCCATGCATAACACAATGAAGTCTAAGTCTCCTCTTCCCTTAACTTTA
CAACATTTAGTGGCTTTTTGGGAAGACATCTCTTTGGCTACTATCAAAGCTGCTTCCCAG
AATATGATTTTTCCAAGTCCTGGTTCCTGTGCAGTTCTTAAAAAGAAAGAGTGTGAGAAA
GAGAATAAGAAGTCCAAAAAGGAAAAAAAGAAAAAAGAAAAGGCAGAAGTTAGGCCCAGG
GGTAATTTGTTTGGAGAGATGGCCCAGCTGGCAGTAGGAGGACCAGAGAAAGATACCATC
TGTGAACTGTGTGGGGAGTCACATCCATACCCGGTGACCTATCACATGAGACAAGCTCAC
CCAGGTTGTGGCCGATATGCTGGTGGACAAGGTTACAATAGCATTGGGCATTTTTGTGGA
GGATGGGCTGGTAACTGTGGTGATGGTGGCATAGGAGGAAGCACTTGGTATCTGGTATGT
GATCGCTGTAGAGAAAAATACCTCCGCGAAAAACAGGCTGCTGCAAGGGAGAAGGTCAAA
CAATCTAGGAGAAAACCAATGCAAGTCAAGACCCCTCGTGCCTTGCCCACCATGGAAGCT
CACCAGGTGATTAAAGCCAATGCACTCTTCCTGCTGTCCCTGAGCAGTGCAGCAGAACCG
AGCATTCTGTGTTACCATCCTGCAAAGCCATTCCAATCTCAGTTGCCCAGTGTAAAAGAA
GGCATTTCTGAGGATCTTCCTGTGAAAATGCCTTGTCTCTACCTGCAGACATTAGCTAGG
CATCATCATGAAAATTTTGTGGGCTATCAAGATGACAATCTATTCCAGGATGAAATGAGA
TATCTACGTTCAACATCTGTACCTGCCCCGTATATATCAGTAACTCCTGATGCAAGTCCT
AATGTATTTGAAGAGCCAGAGAGCAATATGAAGTCTATGCCACCAAGTTTAGAAACCAGT
CCCATAACTGATACTGATCTTGCAAAGAGAACTGTCTTCCAAAGATCATACTCAGTTGTT
GCTTCCGAATATGATAAACAACACTCCATTTTACCTGCACGAGTTAAAGCTATTCCTAGA
AGAAGAGTTAACAGTGGAGACACTGAAGTTGGTTCTTCCCTTTTGAGACATCCGTCTCCT
GAGCTTTCTCGGCTAATCTCAGCCCACAGCTCTCTTTCTAAAGGAGAACGAAATTTCCAG
TGGCCAGTTTTAGCTTTTGTTATACAACATCATGATCTAGAAGGTCTTGAAATAGCAATG
AAACAGGCCCTAAGGAAATCTGCTTGTCGAGTTTTTGCTATGGAGGCTTTCAACTGGCTT
CTGTGTAATGTCATCCAAACCACTTCTCTCCATGATATTCTGTGGCATTTTGTGGCATCA
CTGACTCCTGCACCAGTGGAACCAGAGGAAGAAGAGGATGAAGAAAATAAAACAAGCAAA
GAAAATTCAGAACAAGAGAAAGATACAAGAGTATGTGAACATCCACTCTCAGACATAGTG
ATTGCCGGGGAAGCTGCTCATCCTTTACCACACACCTTTCACCGCTTGCTGCAGACCATC
TCAGACCTTATGATGTCTCTCCCCAGCGGCAGTTCATTACAGCAAATGGCCCTGAGGTGC
TGGAGTCTCAAATTCAAGCAATCTGATCACCAGTTCCTTCATCAGAGCAACGTCTTTCAT
CACATTAACAATATTTTGTCAAAGTCAGATGATGGCGATAGTGAAGAGAGTTTTAGCATC
AGTATACAGTCTGGCTTTGAAGCTATGAGTCAGGAATTATGCATAGTAATGTGCTTAAAG
GACTTAACCAGCATTGTTGACATAAAAACTTCAAGCCGACCTGCCATGATTGGCAGTTTG
ACAGACGGCTCCACAGAAACCTTTTGGGAATCAGGAGATGAAGATAAAAACAAAACTAAG
AACATCACCATCAACTGTGTAAAAGGAATCAATGCCCGCTATGTGTCTGTTCACGTGGAC
AATTCCCGAGATCTTGGGAATAAAGTTACCTCAATGACCTTCTTAACTGGCAAAGCAGTA
GAAGATTTGTGCAGAATAAAGCAGGTTGATCTGGATTCCAGGCACATTGGCTGGGTAACA
AGTGAACTTCCAGGAGGGGATAATCACATCATAAAAATTGAATTAAAAGGCCCAGAAAAT
ACACTGAGAGTTCGACAAGTCAAAGTCCTGGGCTGGAAAGATGGTGAAAGCACAAAAATA
GCTGGCCAGATTTCAGCCAGTGTGGCCCAGCAGAGGAACTGTGAAGCTGAGACTCTGCGA
GTATTCAGACTGATTACGTCTCAAGTATTTGGAAAGCTCATCTCTGGAGATGCTGAACCT
ACACCAGAACAAGAGGAAAAAGCACTATTGTCATCACCTGAAGGAGAAGAAAAAGTATAC
AATGCAACATCAGATGCTGACCTGAAAGAACATATGGTTGGAATCATATTCAGCAGGAGT
AAGCTGACTAACTTACAAAAACAGGTGTGTGCTCATATTGTCCAAGCTATTCGCATGGAA
GCTACCAGAGTCCGTGAAGAATGGGAACATGCTATATCAAGCAAAGAAAATGCCAATTCT
CAGCCAAATGATGAAGATGCCTCCTCTGATGCCTACTGCTTTGAGCTGCTCTCTATGGTT
TTAGCACTGAGTGGCTCTAACGTTGGCCGGCAATATCTGGCTCAACAGCTAACCCTGCTT
CAGGATCTCTTCTCGCTGCTTCACACAGCCTCTCCTAGAGTCCAGAGACAGGTAACCTCT
TTACTAAGAAGAGTTTTGCCTGAAGTAACCCCTAGTCGTCTGGCCAGCATCATAGGAGTG
AAATCCCTCCCCCCAGCAGATATCAGTGATATCATTCACTCAACAGAGAAAGGAGACTGG
AATAAGCTGGGTATCTTGGACATGTTTCTAGGATGCATTGCCAAAGCACTCACTGTACAG
CTAAAAGCCAAAGGAACCACCATCACTGGAACAGCTGGTACCACTGTGGGCAAAGGAGTT
ACAACAGTTACTCTTCCGATGATTTTCAATTCCAGTTATCTCCGACGAGGTGAAAGTCAT
TGGTGGATGAAGGGCTCAACCCCTACCCAGATCTCAGAGATCATCATTAAACTTATCAAG
GATATGGCAGCAGGTCATCTGTCAGAAGCTTGGTCCCGAGTGACAAAAAATGCTATTGCA
GAAACCATCATTGCCTTGACCAAGATGGAAGAAGAATTTAGGTCTCCAGTGAGATGTATT
GCAACAACTAGACTCTGGCTTGCTCTCGCATCCCTATGTGTTCTTGATCAGGACCACGTA
GATCGTCTCTCCTCGGGGAGATGGATGGGAAAGGATGGACAACAAAAACAAATGCCTATG
TGTGATAACCATGATGATGGTGAAACTGCAGCAATCATTTTATGCAATGTCTGTGGAAAT
TTATGTACAGACTGTGACAGATTCCTTCACCTTCATCGAAGAACCAAAACTCATCAAAGA
CAGGTCTTCAAAGAAGAAGAAGAAGCTATAAAGGTTGACCTTCATGAAGGTTGTGGTAGA
ACCAAATTGTTCTGGTTGATGGCACTGGCAGATTCTAAAACAATGAAGGCAATGGTGGAA
TTCCGAGAACACACAGGCAAACCCACCACGAGTAGCTCAGAAGCATGTCGCTTCTGTGGT
TCCAGGAGTGGAACAGAGTTATCTGCTGTTGGCAGTGTTTGTTCTGATGCAGATTGCCAG
GAATACGCTAAGATAGCCTGTAGTAAGACGCATCCTTGTGGCCATCCATGCGGGGGTGTT
AAAAACGAAGAGCACTGTCTGCCCTGTCTACACGGCTGTGACAAAAGTGCCACAAGCCTG
AAGCAAGACGCCGATGACATGTGCATGATATGTTTCACCGAAGCGCTCTCGGCAGCACCA
GCCATTCAGCTGGATTGTAGTCACATATTCCACTTACAGTGCTGTCGGCGAGTATTAGAA
AATCGATGGCTTGGCCCAAGGATAACATTTGGATTTATATCTTGTCCCATTTGCAAGAAC
AAAATTAATCACATAGTACTAAAAGACCTACTTGATCCAATAAAAGAACTCTATGAGGAT
GTCAGAAGAAAAGCCTTAATGAGATTGGAATATGAAGGTCTGCATAAGAGTGAAGCTATC
ACAACTCCTGGTGTGAGGTTTTATAATGACCCAGCTGGCTATGCAATGAATAGATATGCA
TATTATGTGTGCTACAAATGCAGAAAGGCATATTTTGGTGGTGAAGCTCGCTGCGATGCT
GAGGCTGGACGGGGAGATGATTATGATCCCAGAGAGCTCATTTGTGGTGCCTGTTCTGAT
GTTTCCAGGGCTCAGATGTGTCCCAAACATGGCACAGACTTTTTGGAATATAAATGTCGC
TACTGCTGTTCAGTGGCTGTTTTTTTCTGTTTTGGAACAACACATTTTTGTAATGCTTGT
CATGATGATTTTCAAAGAATGACTAGCATTCCTAAGGAAGAACTACCACACTGTCCTGCA
GGTCCCAAAGGCAAGCAGTTAGAAGGAACTGAATGTCCACTCCATGTTGTTCATCCACCC
ACTGGGGAAGAGTTTGCTCTGGGATGTGGAGTGTGCAGAAATGCCCACACTTTTTAG

Protein Properties

Number of Residues

4640

Molecular Weight

510079.5

Theoretical pI

7.03

Pfam Domain Function

RCC1 (PF00415 )
Filamin (PF00630 )
PHR (PF08005 )

Signals

None

Transmembrane Regions

None

Protein Sequence

>Probable E3 ubiquitin-protein ligase MYCBP2
MPVPDGSVAAAGLGLGLPAADSRGHYQLLLSGRALADRYRRIYTAALNDRDQGGGSAGHP
ASRNKKILNKKKLKRKQKSKSKVKTRSKSENLENTVIIPDIKLHSNPSAFNIYCNVRHCV
LEWQKKEISLAAASKNSVQSGESDSDEEEESKEPPIKLPKIIEVGLCEVFELIKETRFSH
PSLCLRSLQALLNVLQGQQPEGLQSEPPEVLESLFQLLLEITVRSTGMNDSTGQSLTALS
CACLFSLVASWGETGRTLQAISAILTNNGSHACQTIQVPTILNSLQRSVQAVLVGKIQIQ
DWFSNGIKKAALMHKWPLKEISVDEDDQCLLQNDGFFLYLLCKDGLYKIGSGYSGTVRGH
IYNSTSRIRNRKEKKSWLGYAQGYLLYRDVNNHSMTAIRISPETLEQDGTVMLPDCHTEG
QNILFTDGEYINQIAASRDDGFVVRIFATSTEPVLQQELQLKLARKCLHACGISLFDLEK
DLHIISTGFDEESAILGAGREFALMKTANGKIYYTGKYQSLGIKQGGPSAGKWVELPITK
SPKIVHFSVGHDGSHALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGK
IVVYTACNNGSSSVISKDGELYMFGKDAIYSDSSSLVTDLKGHFVTQVAMGKAHTCVLMK
NGEVWTFGVNNKGQCGRDTGAMNQGGKGFGVENMATAMDEDLEEELDEKDEKSMMCPPGM
HKWKLEQCMVCTVCGDCTGYGASCVSSGRPDRVPGGICGCGSGESGCAVCGCCKACAREL
DGQEARQRGILDAVKEMIPLDLLLAVPVPGVNIEEHLQLRQEEKRQRVIRRHRLEEGRGP
LVFAGPIFMNHREQALARLRSHPAQLKHKRDKHKDGSGERGEKDASKITTYPPGSVRFDC
ELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQVTA
GSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRKATWIGASG
DQTFLRIDEALINSHVLATSEIFASKHIIGLVPASISEPPPFKCLLINKVDGSCKTFNDS
EQEDLQGFGVCLDPVYDVIWRFRPNTRELWCYNAVVADARLPSAADMQSRCSILSPELAL
PTGSRALTTRSHAALHILGCLDTLAAMQDLKMGVASTEEETQAVMKVYSKEDYSVVNRFE
SHGGGWGYSAHSVEAIRFSADTDILLGGLGLFGGRGEYTAKIKLFELGPDGGDHETDGDL
LAETDVLAYDCAAREKYAMMFDEPVLLQAGWWYVAWARVSGPSSDCGSHGQASITTDDGV
VFQFKSSKKSNNGTDVNAGQIPQLLYRLPTSDGSASKGKQQTSEPVHILKRSFARTVSVE
CFESLLSILHWSWTTLVLGVEELRGLKGFQFTATLLDLERLRFVGTCCLRLLRVYTCEIY
PVSATGKAVVEETSKLAECIGKTRTLLRKILSEGVDHCMVKLDNDPQGYLSQPLSLLEAV
LQECHNTFTACFHSFYPTPALQWACLCDLLNCLDQDIQEANFKTSSSRLLAAVMSALCHT
SVKLTSIFPIAYDGEVLLRSIVKQVSTENDSTLVHRFPLLVAHMEKLSQSEENISGMTSF
REVLEKMLVIVVLPVRNSLRRENELFSSHLVSNTCGLLASIVSELTASALGSEVDGLNSL
HSVKASANRFTKTSQGRSWNTGNGSPDAICFSVDKPGIVVVGFSVYGGGGIHEYELEVLV
DDSEHAGDSTHSHRWTSLELVKGTYTTDDSPSDIAEIRLDKVVPLKENVKYAVRLRNYGS
RTANGDGGMTTVQCPDGVTFTFSTCSLSSNGTNQTRGQIPQILYYRSEFDGDLQSQLLSK
ANEEDKNCSRALSVVSTVVRASKDLLHRALAVDADDIPELLSSSSLFSMLLPLIIAYIGP
VAAAIPKVAVEVFGLVQQLLPSVAILNQKYAPPAFNPNQSTDSTTGNQPEQGLSACTTSS
HYAVIESEHPYKPACVMHYKVTFPECVRWMTIEFDPQCGTAQSEDVLRLLIPVRTVQNSG
YGPKLTSVHENLNSWIELKKFSGSSGWPTMVLVLPGNEALFSLETASDYVKDDKASFYGF
KCFAIGYEFSPGPDEGVIQLEKELANLGGVCAAALMKKDLALPIGNELEEDLEILEEAAL
QVCKTHSGILGKGLALSHSPTILEALEGNLPLQIQSNEQSFLDDFIACVPGSSGGRLARW
LQPDSYADPQKTSLILNKDDIRCGWPTTITVQTKDQYGDVVHVPNMKVEVKAVPVSQKKM
SLQQDQAKKPQRIPGSPAVTAASSNTDMTYGGLASPKLDVSYEPMIVKEARYIAITMMKV
YENYSFEELRFASPTPKRPSENMLIRVNNDGTYCANWTPGAIGLYTLHVTIDGIEIDAGL
EVKVKDPPKGMIPPGTQLVKPKSEPQPNKVRKFVAKDSAGLRIRSHPSLQSEQIGIVKVN
GTITFIDEIHNDDGVWLRLNDETIKKYVPNMNGYTEAWCLSFNQHLGKSLLVPVDESKTN
TDDFFKDINSCCPQEATMQEQDMPFLRGGPGMYKVVKTGPSGHNIRSCPNLRGIPIGMLV
LGNKVKAVGEVTNSEGTWVQLDQNSMVEFCESDEGEAWSLARDRGGNQYLRHEDEQALLD
QNSQTPPPSPFSVQAFNKGASCSAQGFDYGLGNSKGDRGNISTSSKPASTSGKSELSSKH
SRSLKPDGRMSRTTADQKKPRGTESLSASESLILKSDAAKLRSDSHSRSLSPNHNTLQTL
KSDGRMPSSSRAESPGPGSRLSSPKPKTLPANRSSPSGASSPRSSSPHDKNLPQKSTAPV
KTKLDPPRERSKSDSYTLDPDTLRKKKMPLTEPLRGRSTSPKPKSVPKDSTDSPGSENRA
PSPHVVQENLHSEVVEVCTSSTLKTNSLTDSTCDDSSEFKSVDEGSNKVHFSIGKAPLKD
EQEMRASPKISRKCANRHTRPKKEKSSFLFKGDGSKPLEPAKQAMSPSVAECARAVFASF
LWHEGIVHDAMACSSFLKFHPELSKEHAPIRSSLNSQQPTEEKETKLKNRHSLEISSALN
MFNIAPHGPDISKMGSINKNKVLSMLKEPPLHEKCEDGKTETTFEMSMHNTMKSKSPLPL
TLQHLVAFWEDISLATIKAASQNMIFPSPGSCAVLKKKECEKENKKSKKEKKKKEKAEVR
PRGNLFGEMAQLAVGGPEKDTICELCGESHPYPVTYHMRQAHPGCGRYAGGQGYNSIGHF
CGGWAGNCGDGGIGGSTWYLVCDRCREKYLREKQAAAREKVKQSRRKPMQVKTPRALPTM
EAHQVIKANALFLLSLSSAAEPSILCYHPAKPFQSQLPSVKEGISEDLPVKMPCLYLQTL
ARHHHENFVGYQDDNLFQDEMRYLRSTSVPAPYISVTPDASPNVFEEPESNMKSMPPSLE
TSPITDTDLAKRTVFQRSYSVVASEYDKQHSILPARVKAIPRRRVNSGDTEVGSSLLRHP
SPELSRLISAHSSLSKGERNFQWPVLAFVIQHHDLEGLEIAMKQALRKSACRVFAMEAFN
WLLCNVIQTTSLHDILWHFVASLTPAPVEPEEEEDEENKTSKENSEQEKDTRVCEHPLSD
IVIAGEAAHPLPHTFHRLLQTISDLMMSLPSGSSLQQMALRCWSLKFKQSDHQFLHQSNV
FHHINNILSKSDDGDSEESFSISIQSGFEAMSQELCIVMCLKDLTSIVDIKTSSRPAMIG
SLTDGSTETFWESGDEDKNKTKNITINCVKGINARYVSVHVDNSRDLGNKVTSMTFLTGK
AVEDLCRIKQVDLDSRHIGWVTSELPGGDNHIIKIELKGPENTLRVRQVKVLGWKDGEST
KIAGQISASVAQQRNCEAETLRVFRLITSQVFGKLISGDAEPTPEQEEKALLSSPEGEEK
VYNATSDADLKEHMVGIIFSRSKLTNLQKQVCAHIVQAIRMEATRVREEWEHAISSKENA
NSQPNDEDASSDAYCFELLSMVLALSGSNVGRQYLAQQLTLLQDLFSLLHTASPRVQRQV
TSLLRRVLPEVTPSRLASIIGVKSLPPADISDIIHSTEKGDWNKLGILDMFLGCIAKALT
VQLKAKGTTITGTAGTTVGKGVTTVTLPMIFNSSYLRRGESHWWMKGSTPTQISEIIIKL
IKDMAAGHLSEAWSRVTKNAIAETIIALTKMEEEFRSPVRCIATTRLWLALASLCVLDQD
HVDRLSSGRWMGKDGQQKQMPMCDNHDDGETAAIILCNVCGNLCTDCDRFLHLHRRTKTH
QRQVFKEEEEAIKVDLHEGCGRTKLFWLMALADSKTMKAMVEFREHTGKPTTSSSEACRF
CGSRSGTELSAVGSVCSDADCQEYAKIACSKTHPCGHPCGGVKNEEHCLPCLHGCDKSAT
SLKQDADDMCMICFTEALSAAPAIQLDCSHIFHLQCCRRVLENRWLGPRITFGFISCPIC
KNKINHIVLKDLLDPIKELYEDVRRKALMRLEYEGLHKSEAITTPGVRFYNDPAGYAMNR
YAYYVCYKCRKAYFGGEARCDAEAGRGDDYDPRELICGACSDVSRAQMCPKHGTDFLEYK
CRYCCSVAVFFCFGTTHFCNACHDDFQRMTSIPKEELPHCPAGPKGKQLEGTECPLHVVH
PPTGEEFALGCGVCRNAHTF

External Links

GenBank ID Protein

291190787

UniProtKB/Swiss-Prot ID

O75592

UniProtKB/Swiss-Prot Entry Name

MYCB2_HUMAN

PDB IDs

Not Available

GenBank Gene ID

GeneCard ID

GenAtlas ID

HGNC ID

References

General References

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