Human Metabolome Database: Showing Protein CSAD protein (HMDBP08998)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 metabolite

Identification

HMDB Protein ID

HMDBP08998

Secondary Accession Numbers

14738

Name

CSAD protein

Synonyms

Not Available

Gene Name

CSAD

Protein Type

Enzyme

Biological Properties

General Function

Involved in carboxy-lyase activity

Specific Function

Not Available

Pathways

Not Available

Reactions

Not Available

GO Classification

Function
binding
catalytic activity
lyase activity
carbon-carbon lyase activity
carboxy-lyase activity
cofactor binding
pyridoxal phosphate binding
Process
metabolic process
cellular metabolic process
organic acid metabolic process
oxoacid metabolic process
carboxylic acid metabolic process

Cellular Location

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

12q13.11-q14.3

SNPs

CSAD

Gene Sequence

>1750 bp
CCACGGCTTGCGAGCTACTGAAGCGCTGCCGTCTGTACGGACGACGCTGCGGTCTTTGGG
GCTTGCTCCTACCTGCCAGGCGCGGCCTCCCGCTGGCTCCCTGGCCGCGCGGCGCCTCCT
CCAGGCCCCAGCACACCCTGCCAACCCCACCGCCGCGGCTGCCCCCACCGGGACCGAGGG
TGGCTCACACCTGTGGTCCCAGCACGTTGGGAGGCCGAGGAGCTACCTGTGCACCCTGCC
TCCGGCTCTCCTGAGCAGAGAGATCCTGATGGCTGACTCAGAAGCACTCCCCTCCCTTGC
TGGGGACCCAGTGGCTGTGGAAGCCTTGCTCCGGGCCGTGTTTGGGGTTGTTGTGGATGA
GGCCATTCAGAAAGGAACCAGTGTCTCCCAGAAGGTCTGTGAGTGGAAGGAGCCTGAGGA
GCTGAAGCAGCTGCTGGATTTGGAGCTGCGGAGCCAGGGCGAGTCACAGAAGCAGATCCT
GGAGCGGTGTCGGGCTGTGATTCGCTACAGTGTCAAGACTGGTCACCCTCGGTTCTTCAA
CCAGCTCTTCTCTGGGTTGGATCCCCATGCTCTGGCCGGGCGCATTATCACTGAGAGCCT
CAACACCAGCCAGTACACATATGAAATCGCCCCCGTGTTTGTGCTCATGGAAGAGGAGGT
GCTGAGGAAACTGCGGGCCCTGGTGGGCTGGAGCTCTGGGGACGGAATCTTCTGCCCTGG
TGGCTCCATCTCCAACATGTATGCTGTAAATCTGGCCCGCTATCAGCGCTACCCGGATTG
CAAGCAGAGGGGCCTCCGCACACTGCCGCCCCTGGCCCTATTCACATCGAAGGAGTGTCA
CTACTCCATCCAGAAGGGAGCTGCGTTTCTGGGACTTGGCACCGACAGTGTCCGAGTGGT
CAAGGCTGATGAGAGAGGGAAAATGGTCCCCGAGGATCTGGACAGGCAGATTGGTATGGC
CGAGGCTGAGGGTGCTGTGCCGTTCCTGGTCAGTGCCACCTCTGGCACCACTGTGCTAGG
GGCCTTTGACCCCCTGGAGGCAATTGCTGATGTGTGCCAGCGTCATGGGCTATGGCTGCA
TGTGGATGCTGCCTGGGGTGGGAGCGTCCTGCTGTCACAGACACACAGGCATCTCCTGGA
TGGGATCCAGAGGGCTGACTCTGTGGCCTGGAATCCCCACAAGCTCCTCGCAGCAGGCCT
GCAATGCTCTGCACTTCTTCTCCAGGATACCTCGAACCTGCTCAAGCGCTGCCATGGGTC
CCAGGCCAGCTACCTTTTCCAGCAGGACAAGTTCTACGATGTGGCTCTGGACACGGGAGA
CAAGGTGGTGCAGTGTGGCCGCCGTGTGGACTGTCTGAAGCTGTGGCTCATGTGGAAGGC
ACAGGGCGATCAAGGGCTGGAGCGGCGCATCGACCAGGCCTTTGTCCTTGCCCGGTACCT
GGTGGAGGAAATGAAGAAGCGGGAAGGGTTTGAGCTAGTCATGGAGCCTGAGTTTGTCAA
TGTGTGTTTCTGGTTCGTACCCCCCAGCCTGCGAGGGAAGCAGGAGAGTCCAGATTACCA
CGAAAGGCTGTCAAAGGTGGCCCCCGTGCTCAAGGAGCGCATGGTGAAGGAGGGCTCCAT
GATGATTGGCTACCAGCCCCACGGGACCCGGGGCAACTTCTTCCGTGTGGTTGTGGCCAA
CTCTGCACTGACCTGTGCTGATATGGACTTCCTCCTCAACGAGCTGGAGCGGCTAGGCCA
GGACCTGTGA

Protein Properties

Number of Residues

582

Molecular Weight

64252.3

Theoretical pI

7.5

Pfam Domain Function

Pyridoxal_deC (PF00282 )

Signals

None

Transmembrane Regions

None

Protein Sequence

>CSAD protein
HGLRATEALPSVRTTLRSLGLAPTCQARPPAGSLAARRLLQAPAHPANPTAAAAPTGTEG
GSHLWSQHVGRPRSYLCTLPPALLSREILMADSEALPSLAGDPVAVEALLRAVFGVVVDE
AIQKGTSVSQKVCEWKEPEELKQLLDLELRSQGESQKQILERCRAVIRYSVKTGHPRFFN
QLFSGLDPHALAGRIITESLNTSQYTYEIAPVFVLMEEEVLRKLRALVGWSSGDGIFCPG
GSISNMYAVNLARYQRYPDCKQRGLRTLPPLALFTSKECHYSIQKGAAFLGLGTDSVRVV
KADERGKMVPEDLDRQIGMAEAEGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWLH
VDAAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGS
QASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYL
VEEMKKREGFELVMEPEFVNVCFWFVPPSLRGKQESPDYHERLSKVAPVLKERMVKEGSM
MIGYQPHGTRGNFFRVVVANSALTCADMDFLLNELERLGQDL

External Links

GenBank ID Protein

30354461

UniProtKB/Swiss-Prot ID

Q86V02

UniProtKB/Swiss-Prot Entry Name

Q86V02_HUMAN

PDB IDs

Not Available

GenBank Gene ID

GeneCard ID

GenAtlas ID

HGNC ID

References

General References

Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]