Human Metabolome Database: Showing Protein RANBP2-like and GRIP domain-containing protein 8 (HMDBP08545)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 metabolite

Identification

HMDB Protein ID

HMDBP08545

Secondary Accession Numbers

14258

Name

RANBP2-like and GRIP domain-containing protein 8

Synonyms

Ran-binding protein 2-like 3
RanBP2-like 3
RanBP2L3

Gene Name

RGPD8

Protein Type

Unknown

Biological Properties

General Function

Involved in intracellular transport

Specific Function

Not Available

Pathways

Not Available

Reactions

Not Available

GO Classification

Function
binding
Process
establishment of localization
transport
intracellular transport

Cellular Location

Not Available

Gene Properties

Chromosome Location

Chromosome:2

Locus

2q13

SNPs

RGPD8

Gene Sequence

>5298 bp
ATGAGGCGCAGCAAGGCCGATGTGGAGCGGTACGTCGCCTCGGTGCTGGGTCTCACCCCG
TCGCCTCGACAGAAGTCAATGAAAGGATTCTATTTTGCAAAGCTGTATTATGAAGCTAAA
GAATATGATCTTGCTAAAAAATACATATGTACTTACATTAATGTGCAAGAGAGGGATCCC
AAAGCTCACAGATTTCTGGGTCTTCTTTATGAATTGGAAGAAAACACAGAGAAAGCCGTT
GAATGTTACAGGCGTTCAGTGGAATTAAACCCAACACAAAAAGATCTTGTGTTGAAGATT
GCAGAATTGCTTTGTAAAAATGATGTTACTGATGGAAGAGCAAAATACTGGGTCGAAAGA
GCAGCAAAACTTTTCCCAGGAAGTCCTGCAATTTATAAACTAAAGGAACAGCTTCTAGAT
TGTGAAGGTGAAGATGGATGGAATAAACTTTTTGACTTGATTCAGTCAGAACTTTATGTA
AGACCTGATGACGTCCATGTGAACATCCGGCTAGTGGAGTTGTATCGCTCAACTAAAAGA
TTGAAGGATGCTGTGGCCCACTGCCATGAGGCAGAGAGGAACATAGCTTTGCGTTCAAGT
TTAGAGTGGAATTCGTGTGTTGTACAGACCCTTAAGGAATATCTGGAGTCTTTACAGTGT
TTGGAGTCTGATAAAAGTGACTGGCGAGCAACCAATACAGACTTACTGCTGGCCTATGCT
AATCTTATGCTTCTTACGCTTTCCACTAGAGATGTGCAGGAAAATAGAGAATTACTGGAA
AGTTTTGATAGTGCTCTTCAGTCTGCGAAATCTTCTTTGGGTGGAAATGATGAACTGTCA
GCTACTTTCTTAGAAATGAAAGGACATTTCTATATGTATGCTGGTTCTCTGCTCTTGAAG
ATGGGTCAGCATGGTAATAATGTTCAATGGCGAGCTCTTTCTGAGCTGGCTGCATTGTGC
TATCTCATAGCATTTCAGGTTCCAAGACCAAAGATTAAATTAAGAGAAGGTAAAGCTGGA
CAAAATCTGCTGGAAATGATGGCCTGTGACCGACTGAGCCAATCAGGGCACATGTTGCTA
AGCTTAAGTCGTGGCAAGCAAGATTTCTTAAAAGAGGTTGTTGAAACTTTTGCCAACAAA
ATTGGGCAGTCTGCGTTATATGATGCTCTGTTTTCTAGTCAGTCACCTAAGGATACATCT
TTTCTTGGTAGCGATGATATTGGAAAAATTGATGTACAAGAACCAGAGCTTGAAGATTTG
GCTAGATACGATGTTGGTGCTATTCGAGCACATAATGGTAGTCTTCAGCATCTTACTTGG
CTTGGCTTACAGTGGAATTCATTGCCTGCTTTACCTGGAATCCGAAAATGGCTAAAACAG
CTTTTCCATCGTTTGCCCCATGAAACCTCAAGGCTTGAAACAAATGCGCCTGAATCAATA
TGTATTTTAGATCTTGAAGTATTTCTCCTTGGAGTAGTATATACCAGCCACTTACAATTA
AAGGAGAAATGTAATTCTCACCATAGCTCCTATCAGCCGTTATGCCTGCCCTTTCCTGTG
TGTAAACAGCTTTGTACAGAAAGACAAAAATCTTGGTGGGATGCGGTTTGTACTCTGATT
CACAGAAAAGCAGTACCTGGAAACTTGGCAAAATTGAGACTTCTAGTTCAGCATGAAATA
AACACTCTAAGAGCCCAGGAAAAACATGGCCTTCAACCTGCTCTGCTTGTACATTGGGCA
AAATACCTTCAGAAAACGGGCAGCGGTCTTAATTCTTTTTATGGTCAACTAGAATACATA
GGGAGAAGTGTTCATTATTGGAAGAAAGTTTTGCCATTGTTGAAGATAATAAAGAAGAAC
AGTATTCCTGAACCTATTGATCCTCTGTTTAAACATTTTCATAGTGTAGACATTCAGGCA
TCAGAAATTGTTGAATATGAAGAAGACGCACACATAACTTTTGCTATATTGGATGCAGTA
AATGGAAATATAGAAGATGCTGTGACTGCTTTTGAATCTATAAAAAGTGTTGTTTCTTAT
TGGAATCTTGCACTGATTTTTCACAGGAAGGCAGAAGACATTGAAAATGATGCCCTTTCT
CCTGAAGAACAAGAAGAATGCAGAAATTATCTGACAAAGACCAGGGACTACCTAATAAAG
ATTATAGATGACGGTGATTCAAATCTTTCAGTGGTCAAGAAATTGCCTGTGCCCCTGGAG
TCTGTAAAACAGATGCTTAATTCAGTCATGCAGGAACTCGAAGACTATAGTGAAGGAGGT
CCTCTCTATAAAAATGGTTCTTTGCGAAATGCAGATTCAGAAATAAAACATTCTACACCG
TCTCCTACCAAATATTCACTATCACCAAGTAAAAGTTACAAGTATTCTCCCGAAACACCA
CCTCGATGGACAGAAGATCGGAATTCTTTACTGAATATGATTTGCCAACAAGTAGAGGCC
ATTAAGAAAGAAATGCAGGAGTTGAAACTAAATAGCAGTAAGTCAGCATCCCGTCATCGT
TGGCCCACAGAGAATTATGGACCAGACTCGGTGCCTGATGGATATCAGGGGTCACAGACA
TTTCATGGGGCTCCACTAACAGTTGCAACTACTGGCCCTTCAGTATATTATAGTCAGTCA
CCAGCATATAATTCCCAGTATCTTCTCAGACCAGCAGCTAATGTTACTCCCACAAAGGGT
TCTTCTAATACAGAATTTAAGTCAACCAAAGAAGGATTTTCCATCCCTGTGTCTGCTGAT
GGATTTAAATTTGGCATTTCGGAACCAGGAAATCAAGAAAAGAAAAGGGAAAAGCCTCTT
GAAAATGATACTGGCTTACAGGCTCAGGATATTAGGGGCCGGAAGAAGGGCCGTGGTGTG
ATTTTTGGCCAAACAAGTAGCACTTTTACATTTGCAGATGTTGCAAAATCAACTTCAGGA
GAAGGATTTCAGTTTGGCAAAAAAGACCTCAATTTCAAGGGATTTTCAGGTGCTGGAGAA
AAATTATTCTCATCACGATACGGTAAAATGGCCAATAAAGCAAACACTTCCGGTGACTTT
GAGAAAGATGATGATGCCTATAAGACTGAGGACAGCGATGACATCCATTTTGAACCAGTA
GTTCAAATGCCTGAAAAAGTAGAACTTGTAACAGGAGAAGAAGGTGAAAAAGTTCTGTAT
TCACAGGGGGTAAAACTATTTAGATTTGATGCTGAGGTAAGGCAGTGGAAAGAAAGGGGC
TTGGGGAACTTAAAAATTCTCAAAAACGAGGTCAATGGCAAACTAAGAATGCTGATGCGA
AGAGAACAAGTACTAAAAGTGTGTGCTAATCATTGGATAACGACTACAATGAACCTGAAG
CCCCTCTCTGGATCAGATAGAGCATGGATGTGGTCAGCCAGTGATTTCTCTGATGGTGAT
GCCAAACTAGAGCGGTTGGCAGCAAAATTTAAAACACCAGAGCTGGCTGAAGAATTCAAG
CAGAAATTTGAGGAATGCCAGCGGCTTCTGTTAGACATACCACTTCAAACTCCCCATAAA
CTTGTAGATACTGGCAGAGCTGCCAAGTTAATACAGAGAGCTGAAGAAATGAAGAGTGGA
CTGAAAGATTTCAAAACATTTTTGACAAATGATCAAACAAAAGTCACTGAGGAAGAAAAT
AAGGGTTCAGGTACAGGTGTGGCCGGTGCCTCAGACACAACAATAAAACCCAATGCTGAA
AACACTGGGCCCACATTAGAATGGGATAACTATGACTTAAGGGAAGATGCTTTGGATGAT
AGTGTCAGTAGTAGCTCAGTACATGCTTCTCCATTGGCAAGTAGCCCTGTGAGAAAAAAT
CTTTTCCGCTTTGATGAGTCAACAACAGGATCTAACTTCAGTTTTAAATCTGCTTTGAGT
CTATCTAAGTCTCCTGCCAAGTTGAATCAGAGTGGGACTTCAGTTGGCACTGATGAAGAA
TCTGTTGTTACTCAAGAAGAAGAGAGAGATGGACAGTACTTTGAACCTGTTGTTCCTTTA
CCTGATCTAGTTGAAGTATCCAGTGGTGAGGAAAATGAACAAGTTGTTTTTAGTCACAGG
GCAGAAATCTACAGATATGATAAAGATGTTGGTCAATGGAAAGAAAGGGGCATTGGTGAT
ATAAAGATTTTACAGAATTATGATAATAAGCAAGTTCGTATAGTGATGAGAAGGGACCAA
GTATTAAAACTTTGTGCCAATCACAGAATAACTCCAGACATGAGTTTGCAAAATATGAAA
GGGACAGAAAGAGTATGGGTGTGGACTGCATGTGATTTTGCAGATGGAGAAAGAAAAGTA
GAGCATTTAGCTGTTCGTTTTAAACTACAGGATGTTGCAGACTCGTTTAAGAAAATTTTT
GATGAAGCAAAAACAGCCCAGGAAAAAGATTCTTTGATAACACCTCATGTTTCTCGGTCA
AGCACTCCCAGAGAGTCACCATGTGGCAAAATTGCTGTAGCTGTATTAGAAGAAATCACA
AGAGAGAGGACAGATGTTATTCAGGGTGATGATGTAGCAGATGCAGCTTCAGAAGTTGAA
GTGTCTAGCACATCTGAAACAACAACAAAAGCAGTGGTTTCTCCTCCAAAGTTTGTATTT
GTTTCAGAGTCTGTTAAAAGAATTTTTAGTAGTGAAAAATCAAAACCATTTGCATTTGGC
AACAGTTCTGCCACTGGGTCTTTGTTTGGATTTAGTTTTAATGCACCTTTGAAAAGTAAC
AATAGTGAAACTAGTTCAGTAGCCCAGAGTGGATCTGAAAGCAAAGTGGAACCTAAAAAA
TGTGAACTGTCAAAGAACTCTGATATCGAACAGTCTTCAGATAGCAAAGTCAAAAATCTC
TCTGCTTCCTTTCCAACGGAAGAATCTTCAATCAACTACACATTTAAAACACCAGAAAAG
GAGCCTCCATTATGGCATGCTGAATTTACCAAAGAAGAATTGGTTCAGAAGCTCCGTTCC
ACCACAAAAAGTGCAGATCACTTAAACGGCCTGCTTCGGGAAATAGAGGCAACCAATGCA
GTCCTTATGGAGCAAATTAAGCTTCTCAAAAGTGAAATAAGAAGATTGGAAAGGAATCAA
GAGCGAGAGAAGTCTGCAGCTAACCTGGAATACTTGAAGAACGTCTTGCTGCAGTTCATT
TTCTTGAAGCCAGGTAGTGAAAGAGAGAGACTTCTTCCTGTTATAAATACGATGTTGCAG
CTCAGCCCTGAAGAAAAGGGAAAACTTGCTGCGGTTGCTCAAGATGAGGAAGAAAATCCT
TCCCGTTCTTCTGGATGA

Protein Properties

Number of Residues

1765

Molecular Weight

198991.1

Theoretical pI

6.44

Pfam Domain Function

TPR_1 (PF00515 )
GRIP (PF01465 )
Ran_BP1 (PF00638 )

Signals

None

Transmembrane Regions

None

Protein Sequence

>RANBP2-like and GRIP domain-containing protein 8
MRRSKADVERYVASVLGLTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP
KAHRFLGLLYELEENTEKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWVER
AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKR
LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA
NLMLLTLSTRDVQENRELLESFDSALQSAKSSLGGNDELSATFLEMKGHFYMYAGSLLLK
MGQHGNNVQWRALSELAALCYLIAFQVPRPKIKLREGKAGQNLLEMMACDRLSQSGHMLL
SLSRGKQDFLKEVVETFANKIGQSALYDALFSSQSPKDTSFLGSDDIGKIDVQEPELEDL
ARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHRLPHETSRLETNAPESI
CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPFPVCKQLCTERQKSWWDAVCTLI
HRKAVPGNLAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKYLQKTGSGLNSFYGQLEYI
GRSVHYWKKVLPLLKIIKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDAV
NGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECRNYLTKTRDYLIK
IIDDGDSNLSVVKKLPVPLESVKQMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHSTP
SPTKYSLSPSKSYKYSPETPPRWTEDRNSLLNMICQQVEAIKKEMQELKLNSSKSASRHR
WPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTKG
SSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKREKPLENDTGLQAQDIRGRKKGRGV
IFGQTSSTFTFADVAKSTSGEGFQFGKKDLNFKGFSGAGEKLFSSRYGKMANKANTSGDF
EKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERG
LGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGD
AKLERLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEMKSG
LKDFKTFLTNDQTKVTEEENKGSGTGVAGASDTTIKPNAENTGPTLEWDNYDLREDALDD
SVSSSSVHASPLASSPVRKNLFRFDESTTGSNFSFKSALSLSKSPAKLNQSGTSVGTDEE
SVVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGD
IKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKV
EHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAVLEEIT
RERTDVIQGDDVADAASEVEVSSTSETTTKAVVSPPKFVFVSESVKRIFSSEKSKPFAFG
NSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCELSKNSDIEQSSDSKVKNL
SASFPTEESSINYTFKTPEKEPPLWHAEFTKEELVQKLRSTTKSADHLNGLLREIEATNA
VLMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQ
LSPEEKGKLAAVAQDEEENPSRSSG

External Links

GenBank ID Protein

256600210

UniProtKB/Swiss-Prot ID

O14715

UniProtKB/Swiss-Prot Entry Name

RGPD8_HUMAN

PDB IDs

1XKE

GenBank Gene ID

GeneCard ID

GenAtlas ID

HGNC ID

References

General References

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Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell. 2006 Nov 3;127(3):635-48. [PubMed:17081983 ]
Yu LR, Zhu Z, Chan KC, Issaq HJ, Dimitrov DS, Veenstra TD: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra. J Proteome Res. 2007 Nov;6(11):4150-62. Epub 2007 Oct 9. [PubMed:17924679 ]
Bechtel S, Rosenfelder H, Duda A, Schmidt CP, Ernst U, Wellenreuther R, Mehrle A, Schuster C, Bahr A, Blocker H, Heubner D, Hoerlein A, Michel G, Wedler H, Kohrer K, Ottenwalder B, Poustka A, Wiemann S, Schupp I: The full-ORF clone resource of the German cDNA Consortium. BMC Genomics. 2007 Oct 31;8:399. [PubMed:17974005 ]
Cantin GT, Yi W, Lu B, Park SK, Xu T, Lee JD, Yates JR 3rd: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. J Proteome Res. 2008 Mar;7(3):1346-51. doi: 10.1021/pr0705441. Epub 2008 Jan 26. [PubMed:18220336 ]
Nothwang HG, Rensing C, Kubler M, Denich D, Brandl B, Stubanus M, Haaf T, Kurnit D, Hildebrandt F: Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12. Genomics. 1998 Feb 1;47(3):383-92. [PubMed:9480752 ]