Hmdb loader
Identification
HMDB Protein ID HMDBP07995
Secondary Accession Numbers
  • 13706
Name Secernin-1
Synonyms Not Available
Gene Name SCRN1
Protein Type Unknown
Biological Properties
General Function Involved in dipeptidase activity
Specific Function Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium
Pathways Not Available
Reactions Not Available
GO Classification
Function
catalytic activity
hydrolase activity
peptidase activity
peptidase activity, acting on l-amino acid peptides
exopeptidase activity
dipeptidase activity
Process
metabolic process
macromolecule metabolic process
protein metabolic process
proteolysis
Cellular Location
  1. Cytoplasm
Gene Properties
Chromosome Location Chromosome:7
Locus 7p14.3-p14.1
SNPs SCRN1
Gene Sequence
>1245 bp
ATGGCTGCAGCTCCTCCAAGTTACTGTTTTGTTGCCTTCCCTCCACGTGCTAAGGATGGT
CTGGTGGTATTTGGGAAAAATTCAGCCCGGCCCAGAGATGAAGTGCAAGAGGTTGTGTAT
TTCTCGGCTGCTGATCACGAACCGGAGAGCAAGGTTGAGTGCACTTACATTTCAATCGAC
CAAGTTCCAAGGACCTATGCCATAATGATAAGCAGACCCGCCTGGCTCTGGGGAGCAGAA
ATGGGAGCCAATGAACATGGAGTGTGCATAGCCAATGAAGCCATCAACACCAGAGAGCCA
GCTGCCGAGATAGAAGCCTTGCTGGGGATGGATCTGGTCAGGCTTGGTTTAGAAAGAGGG
GAAACAGCTAAAGAAGCCTTAGATGTCATTGTCTCCTTGTTGGAAGAACATGGACAAGGT
GGGAATTACTTTGAAGATGCAAACTCCTGCCACAGCTTCCAAAGTGCATATCTGATTGTG
GATCGTGATGAAGCCTGGGTGCTCGAGACCATAGGGAAGTACTGGGCTGCCGAGAAAGTC
ACAGAGGGAGTGAGGTGCATTTGCAGTCAGCTTTCGCTCACCACTAAGATGGATGCAGAG
CATCCGGAACTCAGGAGTTACGCTCAGAGCCAAGGTTGGTGGACGGGAGAGGGCGAGTTC
AATTTTTCCGAAGTCTTTTCTCCAGTTGAGGATCATCTAGACTGCGGTGCTGGCAAAGAC
AGCTTAGAAAAACAAGAAGAAAGCATCACAGTGCAGACTATGATGAACACCTTACGGGAC
AAAGCCAGCGGAGTGTGCATAGACTCTGAGTTTTTCCTCACCACAGCCAGTGGAGTGTCT
GTCCTGCCGCAGAATAGAAGCTCTCCGTGCATTCACTACTTCACTGGAACCCCTGATCCT
TCCAGGTCCATATTCAAGCCTTTCATCTTTGTTGATGACGTAAAACTTGTCCCCAAAACA
CAGTCTCCCTGTTTTGGGGATGACGACCCTGCCAAAAAGGAGCCTCGGTTCCAGGAGAAA
CCAGACCGCCGGCATGAGCTGTACAAAGCCCACGAGTGGGCACGTGCCATCATCGAAAGT
GACCAGGAGCAAGGTCGCAAGCTGAGGAGCACCATGCTGGAGCTGGAGAAGCAAGGCCTG
GAAGCCATGGAAGAAATCCTGACCAGCTCCGAGCCACTGGACCCTGCGGAAGTGGGGGAC
CTTTTCTATGACTGTGTTGACACGGAGATTAAGTTCTTTAAGTGA
Protein Properties
Number of Residues 414
Molecular Weight 46381.6
Theoretical pI 4.39
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Secernin-1
MAAAPPSYCFVAFPPRAKDGLVVFGKNSARPRDEVQEVVYFSAADHEPESKVECTYISID
QVPRTYAIMISRPAWLWGAEMGANEHGVCIANEAINTREPAAEIEALLGMDLVRLGLERG
ETAKEALDVIVSLLEEHGQGGNYFEDANSCHSFQSAYLIVDRDEAWVLETIGKYWAAEKV
TEGVRCICSQLSLTTKMDAEHPELRSYAQSQGWWTGEGEFNFSEVFSPVEDHLDCGAGKD
SLEKQEESITVQTMMNTLRDKASGVCIDSEFFLTTASGVSVLPQNRSSPCIHYFTGTPDP
SRSIFKPFIFVDDVKLVPKTQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAIIES
DQEQGRKLRSTMLELEKQGLEAMEEILTSSEPLDPAEVGDLFYDCVDTEIKFFK
GenBank ID Protein 90265801
UniProtKB/Swiss-Prot ID Q12765
UniProtKB/Swiss-Prot Entry Name SCRN1_HUMAN
PDB IDs Not Available
GenBank Gene ID AB071705
GeneCard ID SCRN1
GenAtlas ID SCRN1
HGNC ID HGNC:22192
References
General References
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