Showing Protein Protocadherin gamma-C3 (HMDBP07929)

• 13640

1. PC-43
2. PCDH-gamma-C3
3. Protocadherin-2
4. Protocadherin-43

1. Cell membrane
2. Single-pass type I membrane protein

>2805 bp
ATGGTCCCAGAGGCCTGGAGGAGCGGACTGGTAAGCACCGGGAGGGTAGTGGGAGTTTTG
CTTCTGCTTGGTGCCTTGAACAAGGCTTCCACGGTCATTCACTATGAGATCCCGGAGGAA
AGAGAGAAGGGTTTCGCTGTGGGCAACGTGGTCGCGAACCTTGGTTTGGATCTCGGTAGC
CTCTCAGCCCGCAGGTTCCGGGTGGTGTCTGGAGCTAGCCGAAGATTCTTTGAGGTGAAC
CGGGAGACCGGAGAGATGTTTGTGAACGACCGTCTGGATCGAGAGGAGCTGTGTGGGACA
CTGCCCTCTTGCACTGTAACTCTGGAGTTGGTAGTGGAGAACCCGCTGGAGCTGTTCAGC
GTGGAAGTGGTGATCCAGGACATCAACGACAACAATCCTGCTTTCCCTACCCAGGAAATG
AAATTGGAGATTAGCGAGGCCGTGGCTCCGGGGACGCGCTTTCCGCTCGAGAGCGCGCAC
GATCCCGATGTGGGAAGCAACTCTTTACAAACCTATGAGCTGAGCCGAAATGAATACTTT
GCGCTTCGCGTGCAGACGCGGGAGGACAGCACCAAGTACGCGGAGCTGGTGTTGGAGCGC
GCCCTGGACCGAGAACGGGAGCCTAGTCTCCAGTTAGTGCTGACGGCGTTGGACGGAGGG
ACCCCAGCTCTCTCCGCCAGCCTGCCTATTCACATCAAGGTGCTGGACGCGAATGACAAT
GCGCCTGTCTTCAACCAGTCCTTGTACCGGGCGCGCGTCCTGGAGGATGCACCCTCCGGC
ACGCGCGTGGTACAAGTCCTTGCAACGGATCTGGATGAAGGCCCCAACGGTGAAATTATT
TACTCCTTCGGCAGCCACAACCGCGCCGGCGTGCGGCAACTATTCGCCTTAGACCTTGTA
ACCGGGATGCTGACAATCAAGGGTCGGCTGGACTTCGAGGACACCAAACTCCATGAGATT
TACATCCAGGCCAAAGACAAGGGCGCCAATCCCGAAGGAGCACATTGCAAAGTGTTGGTG
GAGGTTGTGGATGTGAATGACAACGCCCCGGAGATCACAGTCACCTCCGTGTACAGCCCA
GTACCCGAGGATGCCCCTCTGGGGACTGTCATCGCTTTGCTCAGTGTGACTGACCTGGAT
GCTGGCGAGAACGGGCTGGTGACCTGCGAAGTTCCACCGGGTCTCCCTTTCAGCCTTACT
TCTTCCCTCAAGAATTACTTCACTTTGAAAACCAGTGCAGACCTGGATCGGGAGACTGTG
CCAGAATACAACCTCAGCATCACCGCCCGAGACGCCGGAACCCCTTCCCTCTCAGCCCTT
ACAATAGTGCGTGTTCAAGTGTCCGACATCAATGACAACCCTCCACAATCTTCTCAATCT
TCCTACGACGTTTACATTGAAGAAAACAACCTCCCCGGGGCTCCAATACTAAACCTAAGT
GTCTGGGACCCCGACGCCCCGCAGAATGCTCGGCTTTCTTTCTTTCTCTTGGAGCAAGGA
GCTGAAACCGGGCTAGTGGGTCGCTATTTCACAATAAATCGTGACAATGGCATAGTGTCA
TCCTTAGTGCCCCTAGACTATGAGGATCGGCGGGAATTTGAATTAACAGCTCATATCAGC
GATGGGGGCACCCCGGTCCTAGCCACCAACATCAGCGTGAACATATTTGTCACTGATCGC
AATGACAATGCCCCCCAGGTCCTATATCCTCGGCCAGGTGGGAGCTCGGTGGAGATGCTG
CCTCGAGGTACCTCAGCTGGCCACCTAGTGTCACGGGTGGTAGGCTGGGACGCGGATGCA
GGGCACAATGCCTGGCTCTCCTACAGTCTCTTGGGATCCCCTAACCAGAGCCTTTTTGCC
ATAGGGCTGCACACTGGTCAAATCAGTACTGCCCGTCCAGTCCAAGACACAGATTCACCC
AGGCAGACTCTCACGGTCTTGATCAAAGACAATGGGGAGCCTTCGCTCTCCACCACTGCT
ACCCTCACTGTGTCAGTAACCGAGGACTCTCCTGAAGCCCGAGCCGAGTTCCCCTCTGGC
TCTGCCCCCCGGGAGCAGAAAAAAAATCTCACCTTTTATCTACTTCTTTCCCTAATCCTG
GTTTCTGTGGGGTTTGTGGTCACAGTGTTCGGAGTAATCATATTCAAAGTTTACAAGTGG
AAGCAGTCTAGAGACCTATACCGAGCCCCGGTGAGCTCACTGTACCGAACACCAGGGCCC
TCCTTGCACGCGGACGCCGTGCGGGGAGGCCTGATGTCGCCGCACCTTTACCATCAGGTG
TATCTCACCACGGACTCCCGCCCCGGCGACCCGCTGCTGAAGAAACCTGGTGCAGCCAGT
CCACTGGCCAGCCGCCAGAACACGCTGCGGAGCTGTGATCCGGTGTTCTATAGGCAGGTG
TTGGGTGCAGAGAGCGCCCCTCCCGGACAGCAAGCCCCGCCCAACACGGACTGGCGTTTC
TCTCAGGCCCAGAGACCCGGCACCAGCGGCTCCCAAAATGGCGATGACACCGGCACCTGG
CCCAACAACCAGTTTGACACAGAGATGCTGCAAGCCATGATCTTGGCGTCCGCCAGTGAA
GCTGCTGATGGGAGCTCCACCCTGGGAGGGGGTGCCGGCACCATGGGATTGAGCGCCCGC
TACGGACCCCAGTTCACCCTGCAGCACGTGCCCGACTACCGCCAGAATGTCTACATCCCA
GGCAGCAATGCCACACTGACCAACGCAGCTGGCAAGCGGGATGGCAAGGCCCCAGCAGGT
GGCAATGGCAACAAGAAGAAGTCGGGCAAGAAGGAGAAGAAGTAA

• Cadherin (PF00028 )
• Cadherin_2 (PF08266 )

• 1-31

• 694-714

>Protocadherin gamma-C3
MVPEAWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGS
LSARRFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFS
VEVVIQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYF
ALRVQTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDN
APVFNQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLV
TGMLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSP
VPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETV
PEYNLSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLS
VWDPDAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHIS
DGGTPVLATNISVNIFVTDRNDNAPQVLYPRPGGSSVEMLPRGTSAGHLVSRVVGWDADA
GHNAWLSYSLLGSPNQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTA
TLTVSVTEDSPEARAEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW
KQSRDLYRAPVSSLYRTPGPSLHADAVRGGLMSPHLYHQVYLTTDSRRSDPLLKKPGAAS
PLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTW
PNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIP
GSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK

1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
2. Wu Q, Maniatis T: A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell. 1999 Jun 11;97(6):779-90. [PubMed:10380929 ]
3. Sano K, Tanihara H, Heimark RL, Obata S, Davidson M, St John T, Taketani S, Suzuki S: Protocadherins: a large family of cadherin-related molecules in central nervous system. EMBO J. 1993 Jun;12(6):2249-56. [PubMed:8508762 ]
4. Lynch ED, Lee MK, Morrow JE, Welcsh PL, Leon PE, King MC: Nonsyndromic deafness DFNA1 associated with mutation of a human homolog of the Drosophila gene diaphanous. Science. 1997 Nov 14;278(5341):1315-8. [PubMed:9360932 ]