Hmdb loader

Showing Protein Protocadherin alpha-7 (HMDBP07884)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 metabolite
Identification
HMDB Protein ID HMDBP07884
Secondary Accession Numbers
  • 13595
Name Protocadherin alpha-7
Synonyms
  1. PCDH-alpha-7
Gene Name PCDHA7
Protein Type Unknown
Biological Properties
General Function Involved in calcium ion binding
Specific Function Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain
Pathways Not Available
Reactions Not Available
GO Classification
Component
cell part
membrane
plasma membrane
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Process
cellular process
cell adhesion
cell-cell adhesion
homophilic cell adhesion
Cellular Location
  1. Cell membrane
  2. Single-pass type I membrane protein
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs PCDHA7
Gene Sequence 
>2814 bp
ATGGTGTGCCCGAATGGATACGACCCAGGGGGCCGACATCTACTGCTGTTTATTATAATT
CTAGCAGCTTGGGAGGCAGGGAGAGGCCAGCTCCACTACTCGGTCCCCGAGGAGGCTAAA
CATGGCAACTTCGTGGGCCGCATCGCGCAGGACCTGGGGCTGGAGCTGGCGGAGCTGGTG
CCGCGCCTGTTCCGGGCGGTGTGCAAATTCCGTGGGGATCTTCTGGAGGTAAATCTGCAG
AATGGCATTTTGTTTGTGAATTCTCGGATCGACCGCGAGGAGCTGTGCGGGCGGAGCGCG
GAGTGCAGCATCCACCTGGAGGTGATCGTGGAAAGGCCGCTGCAGGTTTTCCATGTGGAC
GTGGAGGTGAAGGACATTAACGACAACCCTCCGGTGTTCCCAGCGACACAAAGGAATCTG
TTCATCGCGGAATCCAGGCCGCTTGACTCTCGGTTTCCACTAGAGGGCGCGTCCGATGCA
GATATCGGGGAGAACGCCCTGCTCACTTACAGACTGAGCCCCAATGAGTATTTCTTCCTG
GACGTGCCAACCAGCAACCAGCAGGTAAAACCTCTTGGACTTGTATTACGGAAACTTTTA
GACAGAGAAGAAACTCCGGAGCTTCATTTATTGCTCACGGCCACCGATGGAGGCAAACCC
GAGCTGACTGGCACCGTTCAATTACTCATCACGGTACTGGACAACAATGACAATGCCCCA
GTGTTCGACAGAACCCTGTATACGGTGAAATTACCAGAAAACGTTTCTATCGGAACGCTG
GTGATTCACCCCAATGCCTCAGATTTAGACGAAGGCTTGAATGGGGATATTATTTACTCC
TTCTCCAGTGATGTTTCTCCAGATATAAAATCCAAGTTCCACATGGACCCCTTAAGTGGG
GCAATCACAGTGATAGGACATATGGATTTTGAAGAAAGTAGAGCACACAAGATCCCAGTC
GAGGCTGTCGATAAAGGCTTCCCACCCCTGGCTGGTCATTGTACAGTTCTTGTGGAAGTT
GTGGATGTAAATGACAATGCTCCACAGTTGACTCTCACTTCCCTGTCTCTCCCTATTCCA
GAGGACGCCCAACCAGGTACCGTCATCACATTGATTAGCGTGTTTGACCGAGATTTTGGA
GTCAACGGACAGGTTACCTGCTCCCTGACGCCCCGCGTTCCCTTCAAGTTGGTGTCCACC
TTCAAGAATTACTATTCATTGGTGCTGGACAGCGCTCTGGACCGCGAGAGTGTGTCCGCC
TATGAGCTGGTGGTTACCGCGCGGGACGGGGGCTCGCCTTCTCTGTGGGCCACTGCTAGC
GTGTCCGTGGAGGTGGCCGACGTGAACGACAACGCCCCGGCGTTCGCGCAGCCCGAGTAT
ACGGTGTTCGTGAAGGAGAACAACCCGCCGGGCTGCCACATCTTCACTGTGTCGGCGGGG
GACGCGGACGCGCAGAAGAACGCGCTGGTGTCCTACTCGCTGGTGGAGCTGCGGGTGGGC
GAGCGCGCGCTGTCGAGCTACGTGTCAGTGCACGCGGAGAGCGGCAAGGTGTACGCGCTG
CAGCCGTTGGACCACGAGGAGCTGGAGCTGTTGCAGTTCCAGGTGAGCGCGCGCGATGCG
GGCGTGCCGCCTCTGGGCAGCAACGTGACGCTGCAGGTGTTCGTGCTGGACGAGAACGAC
AACGCGCCGGCACTGCTGGCGCCTCGGGTGGGTGGCACTGGTGGCGCAGTGAGAGAGCTT
GTGCCGCGGTCTGTGGGCGCGGGCCATGTGGTGGCGAAGGTACGTGCAGTTGACGCTGAC
TCAGGCTACAACGCGTGGCTTTCGTATGAGTTGCAACCGGTGGCGGCCGGTGCGAGCATC
CCGTTCCGCGTGGGGCTGTACACTGGTGAGATCAGCACGACACGAGCCCTAGATGAGACG
GACGCACCGCGCCACCGCCTTCTGGTGCTTGTGAAGGACCACGGGGAGCCCTCGCTGACA
GCCACAGCCACCGTGCTGGTGTCGCTGGTGGAAAGCGGCCAGGCACCAAAGGCGTCGTCG
CGGGCATCGTTGGGCATTGCAGGCCCAGAGACCGAGCTGGTGGATGTCAACGTGTACCTG
ATCATCGCCATCTGCGCGGTGTCCAGTCTGTTGGTGCTTACCCTGCTGCTGTACACGGCG
TTGCGGTGCTCAGCGCCGTCCTCTGAGGGCGCATGTAGTTTGGTAAAGCCCACTCTGGTG
TGCTCCAGCGCGGTGGGGAGCTGGTCATTCTCCCAGCAGAGGCGGCAGAGGGTGTGCTCT
GGGGAGGGCCCACCCAAGACAGACCTCATGGCCTTCAGTCCCAGCCTTCCTCAGGGTCCA
TCCTCTACAGACAATCCACGACAGCCCAACCCTGACTGGCGTTACTCTGCCTCCCTGAGA
GCAGGCATGCACAGCTCTGTGCACCTAGAGGAGGCTGGCATTCTACGGGCTGGTCCAGGA
GGGCCTGATCAGCAGTGGCCAACAGTATCCAGTGCAACACCAGAACCAGAGGCAGGAGAA
GTGTCCCCTCCAGTCGGTGCGGGTGTCAACAGCAACAGCTGGACCTTTAAATACGGACCA
GGCAACCCCAAACAATCCGGTCCCGGTGAGTTGCCCGACAAATTCATTATCCCAGGATCT
CCTGCAATCATCTCCATCCGGCAGGAGCCTACTAACAGCCAAATTGACAAAAGTGACTTC
ATAACCTTCGGCAAAAAGGAGGAGACCAAGAAAAAGAAGAAAAAGAAGAAGGGTAACAAG
ACCCAGGAGAAAAAAGAGAAAGGGAACAGCACGACTGACAACAGTGACCAGTGA
Protein Properties
Number of Residues 937
Molecular Weight 100864.0
Theoretical pI 4.86
Pfam Domain Function
Signals
  • 1-29
Transmembrane Regions
  • 698-718
Protein Sequence 
>Protocadherin alpha-7
MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV
PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD
VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL
DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP
VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG
AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP
EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA
YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG
DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD
SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT
ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA
LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP
SSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE
VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF
ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
GenBank ID Protein 9256594
UniProtKB/Swiss-Prot ID Q9UN72
UniProtKB/Swiss-Prot Entry Name PCDA7_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_018910.2
GeneCard ID PCDHA7
GenAtlas ID PCDHA7
HGNC ID HGNC:8673
References
General References
  1. Schmutz J, Martin J, Terry A, Couronne O, Grimwood J, Lowry S, Gordon LA, Scott D, Xie G, Huang W, Hellsten U, Tran-Gyamfi M, She X, Prabhakar S, Aerts A, Altherr M, Bajorek E, Black S, Branscomb E, Caoile C, Challacombe JF, Chan YM, Denys M, Detter JC, Escobar J, Flowers D, Fotopulos D, Glavina T, Gomez M, Gonzales E, Goodstein D, Grigoriev I, Groza M, Hammon N, Hawkins T, Haydu L, Israni S, Jett J, Kadner K, Kimball H, Kobayashi A, Lopez F, Lou Y, Martinez D, Medina C, Morgan J, Nandkeshwar R, Noonan JP, Pitluck S, Pollard M, Predki P, Priest J, Ramirez L, Retterer J, Rodriguez A, Rogers S, Salamov A, Salazar A, Thayer N, Tice H, Tsai M, Ustaszewska A, Vo N, Wheeler J, Wu K, Yang J, Dickson M, Cheng JF, Eichler EE, Olsen A, Pennacchio LA, Rokhsar DS, Richardson P, Lucas SM, Myers RM, Rubin EM: The DNA sequence and comparative analysis of human chromosome 5. Nature. 2004 Sep 16;431(7006):268-74. [PubMed:15372022 ]
  2. Wu Q, Maniatis T: A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell. 1999 Jun 11;97(6):779-90. [PubMed:10380929 ]