Hmdb loader
Identification
HMDB Protein ID HMDBP01865
Secondary Accession Numbers
  • 7259
Name Cyclic AMP-responsive element-binding protein 5
Synonyms
  1. CRE-BPa
  2. CREB-5
  3. cAMP-responsive element-binding protein 5
Gene Name CREB5
Protein Type Unknown
Biological Properties
General Function Involved in sequence-specific DNA binding transcription factor activity
Specific Function Binds to the cAMP response element and activates transcription
Pathways Not Available
Reactions Not Available
GO Classification
Component
intracellular
cell part
Function
cation binding
protein dimerization activity
sequence-specific dna binding transcription factor activity
sequence-specific dna binding
dna binding
nucleic acid binding
protein binding
zinc ion binding
transition metal ion binding
binding
metal ion binding
ion binding
Process
biological regulation
regulation of biological process
regulation of metabolic process
regulation of macromolecule metabolic process
regulation of gene expression
regulation of transcription
regulation of transcription, dna-dependent
Cellular Location
  1. Nucleus (Probable)
Gene Properties
Chromosome Location Chromosome:7
Locus 7p15.1
SNPs CREB5
Gene Sequence
>1527 bp
ATGATTTATGAGGAATCCAAGATGAATTTGGAGCAGGAGAGGCCGTTTGTCTGCAGTGCC
CCAGGCTGCTCCCAGCGCTTCCCAACAGAGGACCATCTGATGATTCATAGGCACAAACAT
GAAATGACTTTGAAGTTTCCTTCAATAAAAACAGACAATATGTTATCAGATCAAACTCCG
ACCCCAACGAGATTCCTGAAGAACTGCGAGGAGGTGGGCCTCTTCAGCGAGCTGGACTGC
TCCCTGGAGCACGAGTTCAGGAAGGCTCAGGAAGAGGAGAGCAGCAAGCGGAATATCTCG
ATGCATAATGCAGTTGGTGGGGCCATGACGGGGCCCGGAACTCACCAGCTTAGCAGCGCT
CGGCTGCCCAACCATGACACCAACGTTGTGATTCAGCAAGCCATGCCGTCGCCTCAGTCC
AGCTCTGTCATCACTCAGGCACCTTCCACCAACCGCCAGATCGGGCCTGTCCCAGGCTCT
CTATCTTCTCTGCTACATCTCCACAACAGACAGAGACAGCCCATGCCAGCCTCCATGCCT
GGGACCCTGCCCAACCCTACAATGCCAGGATCTTCCGCCGTCTTGATGCCAATGGAGCGA
CAAATGTCAGTGAACTCCAGCATCATGGGGATGCAAGGTCCAAATCTCAGCAACCCCTGT
GCTTCTCCCCAGGTCCAGCCAATGCATTCAGAAGCCAAAATGAGGTTGAAGGCTGCATTG
ACTCACCACCCTGCTGCCATGTCAAATGGGAACATGAACACCATGGGACACATGATGGAG
ATGATGGGCTCCCGGCAGGACCAGACGCCACACCATCACATGCACTCGCACCCGCATCAG
CACCAGACACTGCCACCCCATCACCCTTACCCACACCAGCACCAGCACCCAGCACACCAT
CCTCACCCTCAACCCCATCACCAGCAGAACCATCCACATCACCACTCCCATTCCCACCTT
CATGCACACCCAGCACATCACCAGACCTCGCCACATCCGCCCCTGCACACCGGCAACCAA
GCACAGGTTTCACCAGCAACACAACAGATGCAGCCAACCCAGACAATACAGCCACCCCAG
CCCACAGGGGGGCGCCGGCGAAGGGTGGTAGACGAGGATCCGGACGAGAGGCGGCGGAAA
TTTCTGGAACGGAACCGGGCAGCTGCCACCCGCTGCAGACAGAAGAGGAAGGTCTGGGTG
ATGTCATTGGAAAAGAAAGCAGAAGAACTCACCCAGACAAACATGCAGCTTCAGAATGAA
GTGTCTATGTTGAAAAATGAGGTGGCCCAGCTGAAACAGTTGTTGTTAACACATAAAGAC
TGCCCAATAACAGCCATGCAGAAAGAATCACAAGGATATCTAAGTCCAGAGAGTAGCCCT
CCTGCTAGTCCTGTCCCAGCTTGCTCCCAGCAACAAGTCATCCAGCATAATACCATCACT
ACTTCCTCATCGGTCAGCGAGGTGGTAGGAAGCTCCACCCTCAGCCAGCTCACCACTCAC
AGAACAGACCTGAATCCGATTCTTTAA
Protein Properties
Number of Residues 508
Molecular Weight 56858.0
Theoretical pI 8.63
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Cyclic AMP-responsive element-binding protein 5
MIYEESKMNLEQERPSVCSAPGCSQRFPTEDHLMIHRHKHEMTLKFPSIKTDNMLSDQTP
TPTRFLKNCEEVGLFSELDCSLEHEFRKAQEEESSKRNISMHNAVGGAMTGPGTHQLSSA
RLPNHDTNVVIQQAMPSPQSSSVITQAPSTNRQIGPVPGSLSSLLHLHNRQRQPMPASMP
GTLPNPTMPGSSAVLMPMERQMSVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAAL
THHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHH
PHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQ
PTGGRRRRVVDEDPDERRRKFLERNRAAATRCRQKRKVWVMSLEKKAEELTQTNMQLQNE
VSMLKNEVAQLKQLLLTHKDCPITAMQKESQGYLSPESSPPASPVPACSQQQVIQHNTIT
TSSSVSEVVGSSTLSQLTTHRTDLNPIL
GenBank ID Protein 59938770
UniProtKB/Swiss-Prot ID Q02930
UniProtKB/Swiss-Prot Entry Name CREB5_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_182898.2
GeneCard ID CREB5
GenAtlas ID CREB5
HGNC ID HGNC:16844
References
General References
  1. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S: Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 2004 Jan;36(1):40-5. Epub 2003 Dec 21. [PubMed:14702039 ]
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