| HMDB0000027 | Tetrahydrobiopterin | 62989-33-7 |  | C9H15N5O3 | 241.2471 241.117489371 | - Sumi-Ichinose C, Urano F, Kuroda R, Ohye T, Kojima M, Tazawa M, Shiraishi H, Hagino Y, Nagatsu T, Nomura T, Ichinose H: Catecholamines and serotonin are differently regulated by tetrahydrobiopterin. A study from 6-pyruvoyltetrahydropterin synthase knockout mice. J Biol Chem. 2001 Nov 2;276(44):41150-60. Epub 2001 Aug 21. [PubMed:11517215 ]
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| HMDB0000038 | Dihydrobiopterin | 6779-87-9 |  | C9H13N5O3 | 239.2312 239.101839307 | - Wang L, Erlandsen H, Haavik J, Knappskog PM, Stevens RC: Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin. Biochemistry. 2002 Oct 22;41(42):12569-74. [PubMed:12379098 ]
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| HMDB0000472 | 5-Hydroxy-L-tryptophan | 4350-09-8 |  | C11H12N2O3 | 220.2246 220.08479226 | Not Available |
| HMDB0000692 | Fe2+ | 15438-31-0 |  | Fe | 55.845 55.934942133 | Not Available |
| HMDB0000929 | L-Tryptophan | 73-22-3 |  | C11H12N2O2 | 204.2252 204.089877638 | - Pavon JA, Fitzpatrick PF: Insights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylation. Biochemistry. 2006 Sep 12;45(36):11030-7. [PubMed:16953590 ]
- Langfort J, Baranczuk E, Pawlak D, Chalimoniuk M, Lukacova N, Marsala J, Gorski J: The effect of endurance training on regional serotonin metabolism in the brain during early stage of detraining period in the female rat. Cell Mol Neurobiol. 2006 Oct-Nov;26(7-8):1327-42. Epub 2006 Aug 1. [PubMed:16897368 ]
- Nakamura K, Hasegawa H: Developmental role of tryptophan hydroxylase in the nervous system. Mol Neurobiol. 2007 Feb;35(1):45-54. [PubMed:17519505 ]
- Invernizzi RW: Role of TPH-2 in brain function: news from behavioral and pharmacologic studies. J Neurosci Res. 2007 Nov 1;85(14):3030-5. [PubMed:17492791 ]
- Neckameyer WS, Coleman CM, Eadie S, Goodwin SF: Compartmentalization of neuronal and peripheral serotonin synthesis in Drosophila melanogaster. Genes Brain Behav. 2007 Nov;6(8):756-69. Epub 2007 Mar 21. [PubMed:17376153 ]
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| HMDB0001377 | Oxygen | 7782-44-7 |  | O2 | 31.9988 31.989829244 | Not Available |
| HMDB0002111 | Water | 7732-18-5 |  | H2O | 18.0153 18.010564686 | Not Available |
| HMDB0002215 | 4a-Carbinolamine tetrahydrobiopterin | 79647-29-3 |  | C9H13N5O3 | 239.2312 239.101839307 | Not Available |
| HMDB0002281 | 4a-Hydroxytetrahydrobiopterin | 1379003-93-6 |  | C9H15N5O4 | 257.25 257.112403983 | Not Available |