Link Details
- Metabolite
- HMDB0000742 (Homocysteine)
- DrugBank ID
- DB01039
- Drug Name
- Fenofibrate
- Effect
- Increase
- Biospecimen
- Blood
- P-value
- Not Available
- Beta Estimator
- Not Available
- Percent Change
- Not Available
- Pearson Correlation Coefficient
- Not Available
- Comments
- Not Available
- Stulc T, Melenovsky V, Grauova B, Kozich V, Ceska R: Folate supplementation prevents plasma homocysteine increase after fenofibrate therapy. Nutrition. 2001 Sep;17(9):721-3. [PubMed:11527658 ]
- Hamilton-Craig I, Kostner KM, Woodhouse S, Colquhoun D: Use of fibrates in clinical practice: Queensland Lipid Group consensus recommendations. Int J Evid Based Healthc. 2012 Sep;10(3):181-90. doi: 10.1111/j.1744-1609.2012.00275.x. [PubMed:22925614 ]
- McCullough PA, Ahmed AB, Zughaib MT, Glanz ED, Di Loreto MJ: Treatment of hypertriglyceridemia with fibric acid derivatives: impact on lipid subfractions and translation into a reduction in cardiovascular events. Rev Cardiovasc Med. 2011;12(4):173-85. doi: 10.3909/ricm0619. [PubMed:22249508 ]
- Dierkes J, Westphal S, Luley C: Serum homocysteine increases after therapy with fenofibrate or bezafibrate. Lancet. 1999 Jul 17;354(9174):219-20. [PubMed:10421307 ]
- Dierkes J, Luley C, Westphal S: Effect of lipid-lowering and anti-hypertensive drugs on plasma homocysteine levels. Vasc Health Risk Manag. 2007;3(1):99-108. [PubMed:17583180 ]
- Giral P, Bruckert E, Jacob N, Chapman MJ, Foglietti MJ, Turpin G: Homocysteine and lipid lowering agents. A comparison between atorvastatin and fenofibrate in patients with mixed hyperlipidemia. Atherosclerosis. 2001 Feb 1;154(2):421-7. [PubMed:11166775 ]
- Milionis HJ, Papakostas J, Kakafika A, Chasiotis G, Seferiadis K, Elisaf MS: Comparative effects of atorvastatin, simvastatin, and fenofibrate on serum homocysteine levels in patients with primary hyperlipidemia. J Clin Pharmacol. 2003 Aug;43(8):825-30. [PubMed:12953339 ]