| HMDBP00581 | Threonine--tRNA ligase, cytoplasmic | P26639 | TARS | 5p13.2 | Enzyme | - Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
- Torres-Larios A, Sankaranarayanan R, Rees B, Dock-Bregeon AC, Moras D: Conformational movements and cooperativity upon amino acid, ATP and tRNA binding in threonyl-tRNA synthetase. J Mol Biol. 2003 Aug 1;331(1):201-11. [PubMed:12875846 ]
- Ruan B, Bovee ML, Sacher M, Stathopoulos C, Poralla K, Francklyn CS, Soll D: A unique hydrophobic cluster near the active site contributes to differences in borrelidin inhibition among threonyl-tRNA synthetases. J Biol Chem. 2005 Jan 7;280(1):571-7. Epub 2004 Oct 26. [PubMed:15507440 ]
- Cusack S, Yaremchuk A, Krikliviy I, Tukalo M: tRNA(Pro) anticodon recognition by Thermus thermophilus prolyl-tRNA synthetase. Structure. 1998 Jan 15;6(1):101-8. [PubMed:9493271 ]
|
| HMDBP00671 | L-serine dehydratase/L-threonine deaminase | P20132 | SDS | 12q24.13 | Enzyme | Not Available |
| HMDBP03110 | Neutral amino acid transporter A | P43007 | SLC1A4 | 2p15-p13 | Unknown | Not Available |
| HMDBP03303 | Threonine synthase-like 1 | Q8IYQ7 | THNSL1 | 10p12.1 | Enzyme | - Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
|
| HMDBP05340 | Monocarboxylate transporter 10 | Q8TF71 | SLC16A10 | 6q21-q22 | Transporter | - Kim DK, Kanai Y, Chairoungdua A, Matsuo H, Cha SH, Endou H: Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. J Biol Chem. 2001 May 18;276(20):17221-8. Epub 2001 Feb 20. [PubMed:11278508 ]
|
| HMDBP07364 | Acetolactate synthase-like protein | A1L0T0 | ILVBL | 19p13.1 | Unknown | Not Available |
| HMDBP08972 | Serine dehydratase-like | Q96GA7 | SDSL | 12q24.13 | Enzyme | Not Available |
| HMDBP09248 | Probable threonine--tRNA ligase 2, cytoplasmic | A2RTX5 | TARSL2 | 15q26.3 | Enzyme | Not Available |
| HMDBP09249 | Threonine--tRNA ligase, mitochondrial | Q9BW92 | TARS2 | 1q21.3 | Enzyme | - Caillet J, Graffe M, Eyermann F, Romby P, Springer M: Mutations in residues involved in zinc binding in the catalytic site of Escherichia coli threonyl-tRNA synthetase confer a dominant lethal phenotype. J Bacteriol. 2007 Oct;189(19):6839-48. Epub 2007 Jul 20. [PubMed:17644600 ]
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